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Prediction of Neurological Recovery in Patients with Hypoxic-ischemic Encephalopathy

Brain & NeuroRehabilitation 2014³â 7±Ç 1È£ p.5 ~ p.9

À±¼­¿¬(Yoon Seo-Yeon) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ÀçȰÀÇÇб³½Ç
±èÁ¦°æ(Kim Je-Kyung) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ÀçȰÀÇÇб³½Ç
±è¿ë¿í(Kim Yong-Wook) - ¿¬¼¼´ëÇб³ Àǰú´ëÇÐ ÀçȰÀÇÇб³½Ç

Abstract

The incidence of hypoxic-ischemic encephalopathy (HIE) is not well known, however, the common causesof hypoxic-ischemic encephalopathy are sudden cardiac arrest, acute respiratory failure and carbonmonoxide poisoning. Due to high metabolic demand, the brain is very susceptible to damage fromdeprivation of blood supply and oxygen delivery. When patients recover from comatose after HIE, thereare various spectrums of neurological outcomes, ranging from vegetative state to good recovery. Variousmethods including neurologic examination, neurophysiologic and biochemical tools, neuroimaging techniquehave been proposed for the prognostic evaluation of HIE. This article reviews the pathophysiology ofHIE and predictive methods for neurological recovery after HIE.

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hypoxic-ischemic encephalopathy, neurological recovery, prediction
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