The Effect of Regular Exercise on Insulin Sensitivity in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Diabetes & Metabolism Journal 2016³â 40±Ç 4È£ p.253 ~ p.271
(Kimberley L. Way) - University of Sydney Faculty of Health Sciences
(Daniel A. Hackett) - University of Sydney Faculty of Health Sciences
(Michael K. Baker) - Catholic University School of Exercise Science
(Nathan A. Johnson) - University of Sydney Faculty of Health Sciences
Abstract
The purpose of this study was to examine the effect of regular exercise training on insulin sensitivity in adults with type 2 diabetes mellitus (T2DM) using the pooled data available from randomised controlled trials. In addition, we sought to determine whether short-term periods of physical inactivity diminish the exercise-induced improvement in insulin sensitivity. Eligible trials included exercise interventions that involved ¡Ã3 exercise sessions, and reported a dynamic measurement of insulin sensitivity. There was a significant pooled effect size (ES) for the effect of exercise on insulin sensitivity (ES, ?0.588; 95% confidence interval [CI], ?0.816 to ?0.359; P<0.001). Of the 14 studies included for meta-analyses, nine studies reported the time of data collection from the last exercise bout. There was a significant improvement in insulin sensitivity in favour of exercise versus control between 48 and 72 hours after exercise (ES, ?0.702; 95% CI, ?1.392 to ?0.012; P=0.046); and this persisted when insulin sensitivity was measured more than 72 hours after the last exercise session (ES, ?0.890; 95% CI, ?1.675 to ?0.105; P=0.026). Regular exercise has a significant benefit on insulin sensitivity in adults with T2DM and this may persist beyond 72 hours after the last exercise session.
Å°¿öµå
Aerobic training, Glucose tolerance test, Hyperinsulinaemic euglycaemic clamp, Insulin resistance, Resistance training
KMID :
1200020160400040253
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)
Regular exercise has a significant benefit on insulin sensitivity.