Èñ¼®ÇÏÁö ¾ÊÀº ½Å¼Ó ÀÀ°íÇü °í³óµµ ThrombinÀÌ ÇÔÀ¯µÈFibrin Glue¸¦ ÀÌ¿ëÇÑ ºÎºÐÃþ ÇǺÎÀ̽ÄÆíÀÇ °íÁ¤
Skin Graft Fixation Using Fast-clotting Fibrin Glue
´ëÇÑâ»óÇÐȸÁö 2014³â 10±Ç 1È£ p.14 ~ p.19
ÇÑÇöÈ£(Han Hyun-Ho) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ¼ºÇü¿Ü°úÇб³½Ç
°Àμ÷(Kang In-Sook) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ¼ºÇü¿Ü°úÇб³½Ç
¹®¼®È£(Moon Suk-Ho) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ¼ºÇü¿Ü°úÇб³½Ç
Abstract
Sutures and staplers have been widely used for graft fixation, and since the 2000s, fibrin has also been used. To use fibrin, autologous blood is collected and processed, or commercial products are diluted to prepare low-concentration fibrin glues, requiring substantial time and effort. For graft fixation, a fast-clotting fibrin sealant containing 400 IU/ml thrombin was used for all subjects. At 5 days postoperatively, and the graft hematoma/seroma incidence and graft dislocation rates were investigated. At 30 days postoperatively, the graft necrosis and graft-take rates were investigated. The surface area was calculated using ImageJ (US National Institutes of Health, Bethesda, MD, USA). The size of the defect area ranged from 3 cm¡¿2 cm to 22 cm¡¿5 cm. At 5 days postoperatively, the mean hematoma/seroma incidence and graft dislocation rates were 7.84% and 1.29%, respectively. At 30 days postoperatively, the graft necrosis and graft-take rates were 0.76% and 99.24%, respectively. When high-concentration fast-clotting fibrin sealants were applied to skin grafts without a dilution process, no difficulty was experienced during the surgery, and the results were similar to those of slow-clotting fibrin sealants with excellent skin graft-take rates.
Å°¿öµå
Fibrin sealant, Thrombin, Split thickness skin graft
KMID :
1190620140100010014
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)