Role of Enhanced Visibility in Evaluating Polyposis Syndromes Using a Newly Developed Contrast Image Capsule Endoscope

Gut and Liver 2012³â 6±Ç 2È£ p.218 ~ p.222

(Ken Hatogai) - Japan Tokyo Saiseikai Central Hospital
(Naoki Hosoe) - Keio University School of Medicine Center for Diagnostic and Therapeutic Endoscopy
(Hiroyuki Imaeda) - Japan Saitama Medical University Department of General Internal Medicine
(Jean-Francois Rey) - France St Laurent du Var Institut Arnault Tzanck
(Sawako Okada) - Keio University School of Medicine Department of Internal Medicine
(Yuka Ishibashi) - Keio University School of Medicine Department of Internal Medicine
(Kayoko Kimura) - Keio University School of Medicine Department of Internal Medicine
(Kazuaki Yoneno) - Keio University School of Medicine Department of Internal Medicine
(Shingo Usui) - Keio University School of Medicine Department of Internal Medicine
(Yosuke Ida) - Keio University School of Medicine Department of Internal Medicine
(Nobuhiro Tsukada) - Japan Tokyo Saiseikai Central Hospital
(Takanori Kanai) - Keio University School of Medicine Department of Internal Medicine
(Toshifumi Hibi) - Keio University School of Medicine Department of Internal Medicine
(Haruhiko Ogata) - Keio University School of Medicine Center for Diagnostic and Therapeutic Endoscopy

Abstract

Background/Aims:A flexible spectral imaging color enhancement system was installed in new capsule software for video capsule endoscopy. Contrast image capsule endoscopy (CICE) is a novel technology using light-emitting diodes selected for the main absorption range of hemoglobin. We assessed the feasibility and diagnostic effi cacy for small bowel surveillance in patients with polyposis syndromes.

Methods:Six patients with polyposis syndromes, four with familial adenomatous polyposis and one each with Cowden syndrome (CS) and Cronkhite-Canada syndrome (CCS) were examined using CICE. We conducted three evaluations to assess the effect on the numbers of the detected polyps; compare polyp diagnostic rates between adenoma and hamartoma; and assess polyp visibility.

Results:The numbers of detected polyps and diagnostic accuracy did not differ signifi cantly between pre-contrast and contrast images. However, 50% of the adenomatous polyps displayed enhanced visibility on contrast images. CICE contrast images exhibited clearly demarcated lesions and improved the visibility of minute structures of adenomatous polyps. Hamartomatous polyp micro-structures in patients with CS and CCS were more clearly visualized on contrast than pre-contrast images.

Conclusions:CICE is an effective tool for enhancing the visibility of polyps in patients with polyposis syndrome.

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Video capsule endoscopy, Image enhanced endoscopy, Contrast image capsule endoscopy, Polyposis syndrome
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