General anesthesia versus sedation with dexmedetomidine for thoracic endovascular aortic repair in 38 patients in multicenter experiences: A retrospective study
Anesthesia and Pain Medicine 2014³â 9±Ç 3È£ p.193 ~ p.200
ÃÖÇý¶õ(Choi Hey-Ran) - Inje University College of Medicine Seoul Paik Hospital Department of Anesthesiology and Pain Medicine
ÀÌ´ë¿ø(Lee Dae-Won) - Inje University Seoul Paik Hospital Department of Anesthesiology and Pain Medicine
±è°æ¿ì(Kim Kyung-Woo) - Inje University Seoul Paik Hospital Department of Anesthesiology and Pain Medicine
¹æ½Ã¶ó(Bang Si-Ra) - Inje University Seoul Paik Hospital Department of Anesthesiology and Pain Medicine
¿À¹Î°æ(Oh Min-Kyung) - Inje University Busan Paik Hospital Department of Pharmacology
±èÁö¿¬(Kim Ji-Yeon) - Inje University Ilsan Paik Hospital Department of Anesthesiology and Pain Medicine
³ë¿µÁø(Ro Young-Jin) - University of Ulsan College of Medicine Asan Medical Center Department of Anesthesiology and Pain Medicine
Abstract
Background: Endovascular stent graft placement is a useful treatment option in lesions of the thoracic aorta. The aim of this study was to assess the possibility of sedation with dexmedetomidine compared with general anesthesia in patients undergoing thoracic endovascular aortic repair (TEVAR) in a multi-center clinical trial.
Methods: Data from 38 patients with thoracic aorta lesions treated by TEVAR between April 2010 and November 2013 were retrospectively collected at two hospitals. General anesthesia or sedation with dexmedetomidine was determined according to the hospital. Demographics, anesthetic recordings, and complications were reviewed.
Results: Stent graft placement was technically successful in all patients. There were no events during the anesthetic period. A total of 38 patients underwent TEVAR; 29 patients received general anesthesia, and 9 received sedation. Dexmedetomidine sedation (loading dose: 0.5?1.0 ¥ìg/kg for 10 min, maintenance: 0.2?0.8 ¥ìg/kg/h) was successfully performed without anesthesia-related complications or mortality. During the procedure, mean arterial pressure, heart rate, and saturation of peripheral oxygen were not statistically different between general anesthesia and dexmedetomidine sedation.
Conclusions: In our study, TEVAR under sedation with dexmedetomidine was shown to be a feasible procedure that was well tolerated without specific complications
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General anesthesia, Morbidity, Mortality, Sedation, Thoracic endovascular aortic repair
KMID :
1155520140090030193
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