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The Relationship between Coronary Risk Factors and Coronary Calcium Score Detected by Computed Tomography Coronary Angiography in Korean Middle Aged Men

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¹Ú½ÂÇö(Park Seung-Hyun) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼ºÃ¢¿øº´¿ø Á÷¾÷ȯ°æÀÇÇаú
±è¿µ¿í(Kim Young-Wook) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼ºÃ¢¿øº´¿ø Á÷¾÷ȯ°æÀÇÇаú
äâȣ(Chae Chang-Ho) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼ºÃ¢¿øº´¿ø Á÷¾÷ȯ°æÀÇÇаú
±èÀÚÇö(Kim Ja-Hyeon) - ¼º±Õ°ü´ëÇб³ Àǰú´ëÇÐ »ï¼ºÃ¢¿øº´¿ø Á÷¾÷ȯ°æÀÇÇаú
°­À±½Ä(Kang Yune-Sik) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¿¹¹æÀÇÇб³½Ç
¹Ú¿ëÈÖ(Park Yong-Whi) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
Á¤¹é±Ù(Jeong Baek-Geun) - °æ»ó´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¿¹¹æÀÇÇб³½Ç

Abstract

º» ¿¬±¸´Â ´ÙÁßÀýÆí ¹æ»ç¼±´ÜÃþÃÔ¿µÀ» ÀÌ¿ëÇÏ¿© °ü»óµ¿¸Æ ¼®È¸È­¿Í ½ÉÇ÷°üÁúȯ À§ÇèÀÎÀÚ¿ÍÀÇ °ü·Ã¼º¿¡ °üÇÏ¿© ¾Ë¾Æº¸±â À§ÇÏ¿© ¼öÇàµÇ¾ú´Ù.
À̸¦ À§ÇÏ¿© Àϰ³ ´ëÇк´¿ø¿¡¼­ 2010³â 1¿ùºÎÅÍ 2011³â 12¿ù±îÁö ´ÙÁßÀýÆí ¹æ»ç¼±´ÜÃþÃÔ¿µÀ» ½ÃÇàÇÑ 30¢¦59¼¼ÀÇ ¼ºÀÎ ³²¼º 5,899¸íÀ» ´ë»óÀ¸·Î ¹®Áø, ¼³¹®, ½Åü°èÃø, Ç÷¾×°Ë»ç µîÀ» ½ÃÇàÇÏ¿´´Ù. ´ÙÁßÀýÆí ¹æ»ç¼±´ÜÃþÃÔ¿µ ¿µ»óÀ» ÅëÇØ ´ë»óÀÚÀÇ °ü»óµ¿¸Æ Ä®½· Á¡¼ö¸¦ È®ÀÎÇϰí, ±âÁ¸ÀÇ ½ÉÇ÷°üÁúȯ À§ÇèÀÎÀÚ¿¡ ´ëÇØ È®ÀÎÇÏ¿´´Ù.
´ë»óÀÚ 5,899¸íÀÇ Æò±Õ °ü»óµ¿¸Æ Ä®½· Á¡¼ö´Â 8.20À̾ú°í, 773¸í(13.1%)¿¡¼­ °ü»óµ¿¸Æ ¼®È¸È­°¡ °üÂûµÇ¾ú´Ù. °ü»óµ¿¸Æ ¼®È¸È­ À¯¹«¿Í ¾Ë·ÁÁø ½ÉÇ÷°üÁúȯ À§ÇèÀÎÀÚ(³ªÀÌ, Ç÷¾Ð, °øº¹Ç÷´ç, ÄÝ·¹½ºÅ×·Ñ, ¾ÆÆ÷Áö¹æ´Ü¹é, ºñ¸¸)´Â À¯ÀÇÇÑ °ü·Ã¼ºÀ» º¸¿´À¸¸ç, ½ÉÇ÷°üÁúȯ ¹ßº´ À§ÇèµµÆò°¡µµ±¸µé°úµµ À¯ÀÇÇÑ °ü·Ã¼ºÀÌ ÀÖ¾ú´Ù. 30-39¼¼, 40-49¼¼, 50-59¼¼ÀÇ ¿¬·É ±º¿¡¼­ °ü»óµ¿¸Æ ¼®È¸È­¿Í Åë°èÀûÀ¸·Î À¯ÀÇÇÑ °ü·Ã ¿äÀÎÀº °¢±â ´Ù¸¥ ¾ç»óÀ» ³ªÅ¸³Â´Ù.
º» ¿¬±¸¸¦ ÅëÇÏ¿© °ü»óµ¿¸Æ ¼®È¸È­¿Í ÀüÅëÀûÀÎ ½ÉÇ÷°üÁúȯ À§ÇèÀÎÀÚ¿ÍÀÇ °ü·Ã¼º ¹× ½ÉÇ÷°üÁúȯ ¹ßº´À§Çèµµ Æò°¡µµ±¸¿ÍÀÇ °ü·Ã¼ºÀ» È®ÀÎÇÒ ¼ö ÀÖ¾ú´Ù. ¶ÇÇÑ ¿¬·É ±º¿¡ µû¶ó °¢±â ´Ù¸¥ ¾ç»óÀÇ À§ÇèÀÎÀÚ¸¦ È®ÀÎÇÒ ¼ö ÀÖ¾ú´Ù. µû¶ó¼­ ÇâÈÄ ½ÉÇ÷°üÁúȯ ¿¹¹æÀ» À§ÇÑ °ü¸®Àü·« ¼ö¸³¿¡ ¿¬·É¿¡ µû¸¥ Â÷À̸¦ °í·ÁÇÑ Á¢±ÙÀÌ ÇÊ¿äÇÒ °ÍÀ¸·Î »ç·áµÈ´Ù.
Objectives: The objective of this study was to investigate the relationship between coronary artery calcification and risk factors of cardiovascular disease with multidetector computed tomography.

Methods: Data were collected from 5,899 males between 30 and 59 years old by interview, survey, physical examination, blood test, and multidetector computed tomography in the university hospital from January 2010 to December 2011. We confirmed the coronary artery calcium scores of subjects by multidetector computed tomography and identified risk factors of cardiovascular disorders. We investigated the relationship between coronary artery calcification and risk factors of cardiovascular disorders.

Results: Mean calcium score of the coronary arteries in 5,899 participants was 8.20, and 773 participants (13.1%) exhibited coronary artery calcification. The presence of coronary artery calcification was correlated to risk factors of cardiovascular disease (age, blood pressure, triglyceride, HDL cholesterol, LDL cholesterol, glucose, Apolipoprotein A-1, Apolipoprotein B, body mass index, waist circumference) and risk assessment tools of cardiovascular disorders. Significant predicted factors of coronary artery calcification had different patterns in each age group (30-39, 40-49, 50-59 years old).

Conclusions: We confirmed the relationship between coronary artery calcification and either typical risk factors of cardiovascular disease or risk assessment tools of cardiovascular disease. In addition, we also observed that the pattern of these factors varied according to age. Therefore, age-related variation needs to be considered in management strategies to prevent cardiovascular disease.

Ű¿öµå

Cardiovascular disease, Multidetector computed tomography, Vascular calcification
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ÁßÀç¹æ¹ý(Intervention Type)
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DOI
KCDÄÚµå
ICD 03
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