Polyostotic Fibrous Dysplasia Mimicking Multiple Bone Metastases in a Patient with Ductal Carcinoma In Situ
Journal of Breast Cancer 2014³â 17±Ç 1È£ p.83 ~ p.87
ÀÌÁØÈ£(Lee Jun-Ho) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Surgery
±è¼º¿ë(Kim Sung-Yong) - Soonchunhyang University Cheonan Hospital Department of Surgery
ÀÌÁ¤¾ð(Lee Jeong-Eon) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Surgery
Á¶ÀºÀ±(Cho Eun-Yoon) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pathology
ÃÖÀ±¶ó(Choi Yoon-La) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pathology
ÃÖÁØ¿µ(Choi Joon-Young) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Nuclear Medicine
ÇѼ±¿í(Han Sun-Wook) - Soonchunhyang University Cheonan Hospital Department of Surgery
±è¼®¿ø(Kim Seok-Won) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Surgery
±æ¿øÈ£(Kil Won-Ho) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Surgery
³²¼®Áø(Nam Seok-Jin) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Surgery
Abstract
Whole-body bone scans and whole body 18F-fluorodeoxyglucose positron emission tomographic/computed tomographic scans are sensitive for detecting bone metastasis in patients with breast cancer. However, it is often difficult to discriminate between bone metastasis and other nonmalignant bone lesions. Polyostotic fibrous dysplasia is a rare disorder characterized by the osteoid medullary cavity filling with fibrous tissue causing bony expansion. We report the case of a 42-year-old female patient with ductal carcinoma in situ, which appeared to have multiple bone metastases on initial work-up images. Subsequently, the bone metastases were identified as polyostotic fibrous dysplasia. The patient underwent modified radical mastectomy and subsequently visited for a second opinion regarding the bony metastases. She underwent right ilium computed tomography-guided biopsy. Pathology was consistent with fibrous dysplasia. This patient received only adjuvant tamoxifen, and 1.5 years later, there was no evidence of recurrence.
Å°¿öµå
Breast neoplasms, Fibrous dysplasia of bone, Neoplasm metastasis, Positron-emission tomography, Whole body imaging
KMID :
1134120140170010083
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