Citrus Fruit Intake and Breast Cancer Risk: A Quantitative Systematic Review
Journal of Breast Cancer 2013³â 16±Ç 1È£ p.72 ~ p.76
¼ÛÁ¤±¹(Song Jung-Kook) - Jeju National University School of Medicine Department of Preventive Medicine
¹èÁ¾¸é(Bae Jong-Myon) - Jeju National University School of Medicine Department of Preventive Medicine
Abstract
Purpose: We investigated the association between dietary intake of citrus fruits and breast cancer risk.
Methods: The PubMed and EMBASE were searched for relevant articles on diet and breast cancer up to January 2012. All of the epidemiological studies that assessed dietary intake of citrus fruits and presented risk estimates of the association between citrus fruits intake and risk of breast cancer were reviewed. Multivariable-adjusted odds ratios (OR) and associated 95% confidence intervals (CI) for highest versus lowest intake of dietary citrus fruits level were extracted. Overall summary OR was calculated by using a fixed-effect meta-analysis.
Results: Six case-control studies out of five articles were eligible. Overall summary OR showed a 10% reduction in risk of breast cancer associated with high intake of citrus fruits (summary OR, 0.90; 95% CI, 0.85-0.96; p<0.001); results were consistent across the studies (I2=0). Visual inspection of the results did not suggest a publication bias.
Conclusion: Pooled results from observational studies showed an inverse association between citrus fruits intake and the risk of breast cancer.
Å°¿öµå
Breast neoplasms, Citrus, Meta-analysis, Prevention
KMID :
1134120130160010072
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)
The results indicate that a higher intake of citrus fruits may decrease breast cancer risks.