Saccadic Palsy after Cardiac Surgery: Serial Neuroimaging Findings during a 6-Year Follow-Up

Journal of Clinical Neurology 2014³â 10±Ç 4È£ p.367 ~ p.370

±èÀºÁÖ(Kim Eun-Joo) - Pusan National University School of Medicine Pusan National University Hospital Department of Neurology
ÃÖ±¤µ¿(Choi Kwang-Dong) - Pusan National University School of Medicine Pusan National University Hospital Department of Neurology
±èÁ¤Àº(Kim Jeong-Eun) - Samsung Noble County Medical Center Department of Neurology
±è¼ºÀå(Kim Seong-Jang) - Pusan National University School of Medicine Pusan National University Hospital Department of Nuclear Medicine
±èÁö¼ö(Kim Ji-Soo) - Seoul National University College of Medicine Seoul National University Bundang Hospital Department of Neurology
±èÁ¾¼º(Kim Jong-Sung) - University of Ulsan College of Medicine Asan Medical Center Department of Neurology
Á¤ÁöÇâ(Jeong Jee-Hyang) - Ewha Womans University School of Medicine Ewha Womans University Mokdong Hospital Department of Neurology

Abstract

Background: Patients who develop horizontal and vertical saccadic palsy after cardiac surgery have rarely been described. Although most such patients exhibit distinct neurological deficits, their brain MRI findings are almost normal. In addition, functional neuroimaging of such patients has never been reported.

Case Report: A 43-year-old woman with dysarthria, dysphagia, and horizontal and vertical saccadic palsy after cardiac surgery was followed up for about 6 years; serial brain MRIs has been performed during this period, including susceptibility-weighted imaging (SWI) and [18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET). Multiple microbleeds in the cerebral cortex, cerebellum, and brainstem, and glucose hypometabolism in the brainstem, cerebellum, and multiple cortical areas.

Conclusions: To the best of our knowledge, this is the first reported case of saccadic palsy after cardiac surgery with serial SWI and [18F]-FDG-PET performed to explore the possible cerebral lesions.

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saccade, cardiac surgery, [18F]-FDG-PET, SWI
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