Baseline heart rate variability in children and adolescents with vasovagal syncope
Korean Journal of Pediatrics 2014³â 57±Ç 4È£ p.193 ~ p.198
½É¼±Èñ(Shim Sun-Hee) - Catholic University Bucheon St. Mary¡¯s Hospital Department of Pediatrics
¹Ú¼±¿µ(Park Sun-Young) - Catholic University Yeouido St. Mary¡¯s Hospital Department of Pediatrics
¹®¼¼³ª(Moon Se-Na) - Catholic University St. Paul¡¯s Hospital Department of Pediatrics
¿ÀÁøÈñ(Oh Jin-Hee) - Catholic University St. Vincent¡¯s Hospital Department of Pediatrics
ÀÌÀ翵(Lee Jae-Young) - Catholic University College of Medicine Seoul St. Mary¡¯s Hospital Department of Pediatrics
±èÇöÈñ(Kim Hyun-Hee) - Catholic University Yeouido St. Mary¡¯s Hospital Department of Pediatrics
ÇÑÁöȯ(Han Ji-Whan) - Catholic University Uijeongbu St. Mary¡¯s Hospital Department of Pediatrics
À̼øÁÖ(Lee Soon-Ju) - Catholic University Yeouido St. Mary¡¯s Hospital Department of Pediatrics
Abstract
Purpose: This study aimed to evaluate the autonomic imbalance in syncope by comparing the baseline heart rate variability (HRV) between healthy children and those with vasovagal syncope.
Methods: To characterize the autonomic profile in children experiencing vasovagal syncope, we evaluated the HRV of 23 patients aged 7?18 years and 20 healthy children. These children were divided into preadolescent (<12 years) and adolescent groups. The following time-domain indices were calculated: root mean square of the successive differences (RMSSD); standard deviation of all average R-R intervals (SDNN); and frequency domain indices including high frequency (HF), low frequency (LF), normalized high frequency, normalized low frequency, and low frequency to high frequency ratio (LF/ HF).
Results: HRV values were significantly different between healthy children and those with syncope. Student t test indicated significantly higher SNDD values (60.46 ms vs. 37.42 ms, P =0.003) and RMSSD (57.90 ms vs. 26.92 ms, P=0.000) in the patient group than in the control group. In the patient group, RMSSD (80.41 ms vs. 45.89 ms, P =0.015) and normalized HF (61.18 ms vs. 43.19 ms, P =0.022) were significantly higher in adolescents, whereas normalized LF (38.81 ms vs. 56.76 ms, P =0.022) and LF/HF ratio (0.76 vs. 1.89, P =0.041) were significantly lower in adolescents. In contrast, the control group did not have significant differences in HRV values between adolescents and preadolescents.
Conclusion: The results of this study indicated that children with syncope had a decreased sympathetic tone and increased vagal tone compared to healthy children. Additionally, more severe autonomic imbalances possibly occur in adolescents than in preadolescents.
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Vasovagal syncope, Heart rate, Child, Adolescent
KMID :
1130320140570040193
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