Aortic valve replacement surgery for a case of infantile Takayasu arteritis

Korean Journal of Pediatrics 2012년 55권 7호 p.254 ~ p.258

권혜원(Kwon Hye-Won) - Seoul National University Children’s Hospital Department of Pediatrics
(Suh Yoon-Jung) - Seoul National University Children’s Hospital Department of Pediatrics
방지석(Bang Ji-Seok) - Seoul National University Children’s Hospital Department of Pediatrics
권보상(Kwon Bo-Sang) - Seoul National University Children’s Hospital Department of Pediatrics
김기범(Kim Gi-Beom) - Seoul National University Children’s Hospital Department of Pediatrics
배은정(Bae Eun-Jung) - Seoul National University Children’s Hospital Department of Pediatrics
김웅한(Kim Woong-Han) - Seoul National University Children’s Hospital Department of Thoracic and Cardiovascular
노정일(Noh Chung-Il) - Seoul National University Children’s Hospital Department of Pediatrics

Abstract

Takayasu arteritis is a chronic inflammatory disease of unknown etiology primarily affecting the aorta and its major branches and usually occurring in the second or third decade of life. Here, we report a case of Takayasu arteritis in a 10-month-old patient. The infant presented with signs of congestive heart failure and severe aortic regurgitation. Echocardiography and computed tomography angiography showed an abnormally dilated thoracic and abdominal aorta. The infant was initially treated with prednisolone, followed by commissuroplasty of the aortic valve but neither approach ameliorated the heart failure. The patient was eventually treated with a mechanical aortic valve replacement surgery at the age of 12 months, and her condition stabilized. Although unusual, this case indicates that the diagnosis of Takayasu arteritis should be considered in children with unexplained systemic symptoms, aortic valve regurgitation, and heart failure. Because severe aortic regurgitation may be a fatal complication of Takayasu arteritis, early aortic valve replacement surgery should be considered, even in very young children.

키워드

Aortic valve insufficiency, Takayasu arteritis
원문 및 링크아웃 정보
등재저널 정보
학술진흥재단(KCI) KoreaMed 대한의학회 회원 
주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
Because AR is a potentially fatal complication of TA, early and aggressive aortic valve replacement surgery with perioperative immunosuppressive therapy should be considered.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
KCD코드
ICD 03
건강보험코드