Improvement of Screening Accuracy of Mini-Mental State Examination for Mild Cognitive Impairment and Non-Alzheimer¡¯s Disease Dementia by Supplementation of Verbal Fluency Performance
Psychiatry Investigation 2014³â 11±Ç 1È£ p.44 ~ p.51
±èÁö¿í(Kim Jee-Wook) - Hallym University Dongtan Sacred Heart Hospital Department of Neuropsychiatry
À̵¿¿µ(Lee Dong-Young) - Seoul National University Hospital Department of Neuropsychiatry
¼ÀºÇö(Seo Eun-Hyun) - Seoul National University Hospital Interdisciplinary Program for Cognitive Science
¼Õº¸°æ(Sohn Bo-Kyung) - Seoul National University Hospital Department of Neuropsychiatry
ÃÖ¿µ¹Î(Choe Young-Min) - Seoul National University Hospital Department of Neuropsychiatry
±è½Å°â(Kim Shin-Gyeom) - Soonchunhyang University Bucheon Hospital Department of Neuropsychiatry
¹Ú½Å¿µ(Park Shin-Young) - Daelim Saint Mary¡¯s Hospital Department of Neuropsychiatry
ÃßÀÏÇÑ(Choo Il-Han) - Chosun University Hospital Department of Neuropsychiatry
À±Á¾Ã¶(Youn Jong-Chul) - Kyunggi Provincial Hospital for Elderly Department of Neuropsychiatry
ÁÖÁøÇü(Jhoo Jin-Hyeong) - Kangwon National University Hospital Department of Neuropsychiatry
±è±â¿õ(Kim Ki-Woong) - Seoul National University Bundang Hospital Department of Neuropsychiatry
¿ìÁ¾ÀÎ(Woo Jong-Inn) - Seoul National University Hospital Department of Neuropsychiatry
Abstract
Objective: This study aimed to investigate whether the supplementation of Verbal Fluency: Animal category test (VF) performance can improve the screening ability of Mini-Mental State Examination (MMSE) for mild cognitive impairment (MCI), dementia and their major subtypes.
Methods: Six hundred fifty-five cognitively normal (CN), 366 MCI [282 amnestic MCI (aMCI); 84 non-amnestic MCI (naMCI)] and 494 dementia [346 Alzheimer¡¯s disease (AD); and 148 non-Alzheimer¡¯s disease dementia (NAD)] individuals living in the community were included (all aged 50 years and older) in the study.
Results: The VF-supplemented MMSE (MMSE+VF) score had a significantly better screening ability for MCI, dementia and overall cognitive impairment (MCI plus dementia) than the MMSE raw score alone. MMSE+VF showed a significantly better ability than MMSE for both MCI subtypes, i.e., aMCI and naMCI. In the case of dementia subtypes, MMSE+VF was better than the MMSE alone for NAD screening, but not for AD screening.
Conclusion: The results support the usefulness of VF-supplementation to improve the screening performance of MMSE for MCI and NAD.
Å°¿öµå
Mini-Mental State Examination, Verbal fluency, Screening accuracy, Mild cognitive impairment, Non-Alzheimer¡¯s disease dementia
KMID :
1118520140110010044
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)