Korean Medication Algorithm for Depressive Disorder: Comparisons with Other Treatment Guidelines

Psychiatry Investigation 2014³â 11±Ç 1È£ p.1 ~ p.11

¿ÕÈñ·É(Wang Hee-Ryung) - Catholic University College of Medicine Yeouido St. Mary¡¯s Hospital Department of Psychiatry
¹Ú¿ø¸í(Bahk Won-Myong) - Catholic University College of Medicine Yeouido St. Mary¡¯s Hospital Department of Psychiatry
¹Ú¿µ¹Î(Park Young-Min) - Inje University College of Medicine Ilsan Paik Hospital Department of Psychiatry
ÀÌȲºó(Lee Hwang-Bin) - Seoul National Hospital Department of Psychiatry
¼ÛÈĸ²(Song Hoo-Rim) - Catholic University College of Medicine Yeouido St. Mary¡¯s Hospital Department of Psychiatry
Á¤Á¾Çö(Jeong Jong-Hyun) - Catholic University College of Medicine St. Vincent¡¯s Hospital Department of Psychiatry
¼­Á¤¼®(Seo Jeong-Seok) - Konkuk University School of Medicine Department of Psychiatry
ÀÓÀº¼º(Lim Eun-Sung) - Shinsegae Hospital
È«Á¤¿Ï(Hong Jeong-Wan) - Namwon Sungil Mental Hospital
±è¿ø(Kim Won) - Inje University College of Medicine Seoul Paik Hospital Department of Psychiatry
Àü´öÀÎ(Jon Duk-In) - Hallym University College of Medicine Department of Psychiatry
È«ÁøÇ¥(Hong Jin-Pyo) - University of Ulsan College of Medicine Department of Psychiatry
¿ì¿µ¼·(Woo Young-Sup) - Catholic University College of Medicine Yeouido St. Mary¡¯s Hospital Department of Psychiatry
¹Î°æÁØ(Min Kyung-Joon) - Chung-Ang University College of Medicine Department of Psychiatry

Abstract

We aimed to compare the recommendations of the Korean Medication Algorithm Project for Depressive Disorder 2012 (KMAP-DD 2012) with other recently published treatment guidelines for depressive disorder. We reviewed a total of five recently published global treatment guidelines and compared each treatment recommendation of the KMAP-DD 2012 with those in other guidelines. For initial treatment recommendations, there were no significant major differences across guidelines. However, in the case of nonresponse or incomplete response to initial treatment, the second recommended treatment step varied across guidelines. For maintenance therapy, medication dose and duration differed among treatment guidelines. Further, there were several discrepancies in the recommendations for each subtype of depressive disorder across guidelines. For treatment in special populations, there were no significant differences in overall recommendations. This comparison identifies that, by and large, the treatment recommendations of the KMAP-DD 2012 are similar to those of other treatment guidelines and reflect current changes in prescription pattern for depression based on accumulated research data. Further studies will be needed to address several issues identified in our review.

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Depressive disorder, Pharmacotherapy, Algorithm, Treatment guideline, KMAP-DD 2012
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