Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A

Korean Journal of Hepatology 2014³â 20±Ç 2È£ p.204 ~ p.207

ÀåÈ¿Á¤(Chang Hyo-Jeong) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine
½Åµ¿Çö(Sinn Dong-Hyun) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine
(Cho Sung-Gyun) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine
¿ÀÅÂÈÆ(Oh Tae-Hoon) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine
ÀüÅÂÁÖ(Jeon Tae-Joo) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine
½Å¿øâ(Shin Won-Chang) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine
ÃÖ¿øÃæ(Choi Won-Choong) - Inje University College of Medicine Inje University Sanggye Paik Hospital Department of Internal Medicine

Abstract

Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepatic manifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-yearold female with a diagnosis of AHA presented with severe anemia (hemoglobin level, 6.9 g/dL) during her clinical course. A diagnostic workup revealed AIHA and PRCA as the cause of the anemia. The patient was treated with an initial transfusion and corticosteroid therapy. Her anemia and liver function test were completely recovered by 9 months after the initial presentation. We review the clinical features and therapeutic strategies for this rare case of extrahepatic manifestation of AHA.

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Hepatitis A, Pure red-cell aplasia, Autoimmune hemolytic anemia
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