ÃÖÇö±Ô(Choi Hyung-Gyu) - Korea Cancer Center Hospital Department of Internal Medicine
º¯Áؼö(Byun Jun-Su) - Korea Cancer Center Hospital Department of Internal Medicine
(Moon Chae-Ho) - Korea Cancer Center Hospital Department of Internal Medicine
À±Á¾È£(Yoon Jong-Ho) - Korea Cancer Center Hospital Department of Internal Medicine
¾ç±â¿µ(Yang Ki-Young) - Korea Cancer Center Hospital Department of Internal Medicine
¹Ú¼öö(Park Su-Cheol) - Korea Cancer Center Hospital Department of Internal Medicine
ÇÑöÁÖ(Han Chul-Ju) - Korea Cancer Center Hospital Department of Internal Medicine
Abstract
An 84-year-old man was admitted to our hospital with fever, jaundice, and itching. He had been diagnosed previously with chronic renal failure and diabetes, and had been taking allopurinol medication for 2 months. A physical examination revealed that he had a fever (38.8¨¬C), jaundice, and a generalized maculopapular rash. Azotemia, eosinophilia, atypical lymphocytosis, elevation of liver enzymes, and hyperbilirubinemia were detected by blood analysis. Magnetic resonance cholangiography revealed multiple cysts similar to choledochal cysts in the liver along the biliary tree. Obstructive jaundice was suspected clinically, and so an endoscopic ultrasound examination was performed, which ruled out a diagnosis of obstructive jaundice. The patient was diagnosed with DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome due to allopurinol. Allopurinol treatment was stopped and steroid treatment was started. The patient died from cardiac arrest on day 15 following admission.
Å°¿öµå
DRESS syndrome, Allopurinol, Jaundice
KMID :
1103920140200010071
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)