Radiofrequency ablation of very-early-stage hepatocellular carcinoma inconspicuous on fusion imaging with B-mode US: value of fusion imaging with contrast-enhanced US

Korean Journal of Hepatology 2014³â 20±Ç 1È£ p.61 ~ p.70

¹ÎÁöÇý(Min Ji-Hye) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
ÀÓÈ¿±Ù(Lim Hyo-Keun) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
ÀÓ»óÇõ(Lim Sang-Hyeok) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
°­Å¿í(Kang Tae-Wook) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
¼Û°æµÎ(Song Kyoung-Doo) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
ÃÖ¼­¿¬(Choi Seo-Youn) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
ÀÓÇöö(Rhim Hyun-Chul) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science
À̹οì(Lee Min-Woo) - Sungkyunkwan University School of Medicine Department of Radiology and Center for Imaging Science

Abstract

Background/Aims: To determine the value of fusion imaging with contrast-enhanced ultrasonography (CEUS) and computed tomography (CT)/magnetic resonance (MR) images for percutaneous radiofrequency ablation (RFA) of very-early-stage hepatocellular carcinomas (HCCs) that are inconspicuous on fusion imaging with B-mode ultrasound (US) and CT/MR images.

Methods: This retrospective study was approved by our institutional review board and the requirement for informed consent was waived. Fusion imaging with CEUS using Sonazoid contrast agent and CT/MR imaging was performed on HCCs (<2 cm) that were inconspicuous on fusion imaging with B-mode US. We evaluated the number of cases that became conspicuous on fusion imaging with CEUS. Percutaneous RFA was performed under the guidance of fusion imaging with CEUS. Technical success and major complication rates were assessed.

Results: In total, 30 patients with 30 HCCs (mean, 1.2 cm; range, 0.6-1.7 cm) were included, among which 25 (83.3%) became conspicuous on fusion imaging with CEUS at the time of the planning US and/or RFA procedure. Of those 25 HCCs, RFA was considered feasible for 23 (92.0%), which were thus treated. The technical success and major complication rates were 91.3% (21/23) and 4.3% (1/23), respectively.

Conclusions: Fusion imaging with CEUS and CT/MR imaging is highly effective for percutaneous RFA of very-earlystage HCCs inconspicuous on fusion imaging with B-mode US and CT/MR imaging.

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Hepatocellular carcinoma, Radiofrequency ablation, Contrast-enhanced ultrasonography, Sonazoid, Fusion imaging
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