육종양 간내 담관암: 증례보고 및 국내 문헌고찰
Sarcomatoid Intrahepatic Cholangiocarcinoma: A Rare Case of Primary Liver Cancer
Journal of Liver Cancer 2016년 16권 2호 p.139 ~ p.144
이두혁(Lee Doo-Hyuck) - 단국대학교 의과대학 내과학교실
한규형(Han Kyu-Hyung) - 단국대학교 의과대학 내과학교실
안선영(Ann Sun-Young) - 단국대학교 의과대학 내과학교실
김상선(Kim Sang-Sun) - 단국대학교 의과대학 내과학교실
신현성(Shin Hyun-Sung) - 단국대학교 의과대학 내과학교실
방기배(Bang Ki-Bae) - 단국대학교 의과대학 내과학교실
최준호(Choi Jun-Ho) - 단국대학교 의과대학 내과학교실
김석배(Kim Suk-Bae) - 단국대학교 의과대학 내과학교실
이원애(Lee Won-Ae) - 단국대학교 의과대학 병리학교실
송일한(Song Il-Han) - 단국대학교 의과대학 내과학교실
Abstract
Sarcomatoid carcinoma arising from intrahepatic cholangiocyte, an extremely rare primary liver cancer, has highly invasive and metastatic potential. The pathogenesis of this tumor is unclear, although histogenetic mechanisms, such as transdifferentiation/dedifferentiation (epithelialmesenchymal transition or metaplastic transformation), biphasic differentiation (combination and collision), and redifferentiation, might be suggested to explain the simultaneous coexistence of carcinoma and sarcoma components in the same tumor. Immunohistochemical staining might be necessary to differentiate whether sarcomatous component is originated from hepatocyte or cholangiocyte. We report a case of sarcomatoid intrahepatic cholangiocarcinoma in a 58 year-old man presenting as an incidentally detected liver mass on regular health examination, which was diagnosed by an application of immunohistochemical methods after surgical resection, with a review of the literature based on 9 cases reported in Korea.
키워드
Sarcomatoid carcinoma, Cholangiocarcinoma, Liver neoplasm
KMID :
1039320160160020139
원문 및 링크아웃 정보
등재저널 정보
유효성결과(Recomendation)
We report a case of sarcomatoid intrahepatic cholangiocarcinoma in a 58 year-old man presenting as an incidentally detected liver mass on regular health examination, which was diagnosed by an application of immunohistochemical methods after surgical resection.