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Sarcomatoid Intrahepatic Cholangiocarcinoma: A Rare Case of Primary Liver Cancer
Journal of Liver Cancer 2016³â 16±Ç 2È£ p.139 ~ p.144
À̵ÎÇõ(Lee Doo-Hyuck) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÇѱÔÇü(Han Kyu-Hyung) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¾È¼±¿µ(Ann Sun-Young) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è»ó¼±(Kim Sang-Sun) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
½ÅÇö¼º(Shin Hyun-Sung) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹æ±â¹è(Bang Ki-Bae) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÃÖÁØÈ£(Choi Jun-Ho) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è¼®¹è(Kim Suk-Bae) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌ¿ø¾Ö(Lee Won-Ae) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç
¼ÛÀÏÇÑ(Song Il-Han) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
Sarcomatoid carcinoma arising from intrahepatic cholangiocyte, an extremely rare primary liver cancer, has highly invasive and metastatic potential. The pathogenesis of this tumor is unclear, although histogenetic mechanisms, such as transdifferentiation/dedifferentiation (epithelialmesenchymal transition or metaplastic transformation), biphasic differentiation (combination and collision), and redifferentiation, might be suggested to explain the simultaneous coexistence of carcinoma and sarcoma components in the same tumor. Immunohistochemical staining might be necessary to differentiate whether sarcomatous component is originated from hepatocyte or cholangiocyte. We report a case of sarcomatoid intrahepatic cholangiocarcinoma in a 58 year-old man presenting as an incidentally detected liver mass on regular health examination, which was diagnosed by an application of immunohistochemical methods after surgical resection, with a review of the literature based on 9 cases reported in Korea.
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Sarcomatoid carcinoma, Cholangiocarcinoma, Liver neoplasm
KMID :
1039320160160020139
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À¯È¿¼º°á°ú(Recomendation)
We report a case of sarcomatoid intrahepatic cholangiocarcinoma in a 58 year-old man presenting as an incidentally detected liver mass on regular health examination, which was diagnosed by an application of immunohistochemical methods after surgical resection.