Vaccine adjuvant materials for cancer immunotherapy and control of infectious disease

Clinical and Experimental Vaccine Research 2015³â 4±Ç 1È£ p.54 ~ p.58

ÀÓ¿ëÅÃ(Lim Yong-Taik) - Sungkyunkwan University School of Chemical Engineering SKKU Advanced Institute of Nanotechnology

Abstract

Adjuvants can be defined as pharmacological and immunological components that are able to modify and/or enhance antigen-specific immune responses. Based on the interdisciplinary research between immunology and material science/engineering, various vaccine adjuvant materials have been developed. By rational design and engineering of antigen or adjuvant materials, immune-modulatory vaccine systems generated to activate immune system. Here, we review the current progress of bioengineered prophylactic and/or therapeutic vaccine adjuvant for cancer and/or infectious disease, and discuss the prospect of future vaccine adjuvant materials.

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Immunological adjuvants, Immunotherapy, Immunomodulation
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