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반복되는 천명을 주소로 내원한 3세 미만의 환아에서 25-hydroxyvitamin D의 혈청 내 농도와 관련된 인자
Factors associated with serum vitamin D levels in children with recurrent wheezing less than 3 years old

Allergy Asthma & Respiratory Disease 2014년 2권 4호 p.293 ~ p.297

최은정(Choi Eun-Jeong) - 일신기독병원 소아청소년과
박누리(Bak Nu-Ri) - 동아대학교 의과대학 소아과학교실
정진아(Jung Jin-A) - 동아대학교 의과대학 소아과학교실
김대철(Kim Dae-Cheol) - 동아대학교 의과대학 병리학교실
안혜성(Ahn Hye-Sung) - 온종합병원 소아청소년과
윤현진(Yun Hyun-Jin) - 일신기독병원 소아청소년과

Abstract

Purpose: We evaluated the relationship between laboratory/clinical factors and vitamin D levels in recurrent wheezers less than 3 years old.

Methods: We retrospectively analyzed clinical data and laboratory factors (25-hydroxyvitamin D, complete blood count, C-reactive protein, glutamic oxaloacetic transaminase, glutamyl purovic transaminase, alkaline phosphatase [ALP], eosinophil counts, and serum IgE IgG, IgA, IgM) of 84 children less than 3 years who had experienced wheezing episodes at least 3 times.

Results: Children in the normal group (1.4±0.9 years) were younger than those in the deficient (2.2±1.2 years) and insuffient (2.3±1.0 years) groups (P=0.010). Glutamyl purovic transaminase were higher in the normal group (24.5±19.4 IU/L) than in the deficient (16.0±4.7 IU/L) and insufficient (15.3±4.5 IU/L) groups (P=0.009). ALP were higher in the deficient (791.4±180.8 IU/L) and insufficient (770.4±251.2 IU/L) groups than in the normal group (631.9±127.0 IU/L, P=0.034). Total IgE levels were higher in the deficient group (171.9±212.1 kU/L) than in the normal group (43.7±58.3 kU/L, P<0.05), and the rate of sensitization to aeroallergens was higher in the insufficient group (36.1%) than in the normal group (10%, P<0.05).

Conclusion: Among children with recurrent wheezing less than 3 years old, low vitamin D levels may be associated with older age, total IgE, ALP level, glutamic pyruvate transaminase level, and rate of sensitization to aeroallergens

키워드

Vitamin D, Asthma, Wheezing, Young childhood

KMID : 1035620140020040293

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주제코드

주제명(Target field)

연구대상(Population)

연구참여(Sample size)

대상성별(Gender)

질병특성(Condition Category)

연구환경(Setting)

연구설계(Study Design)

연구기간(Period)

중재방법(Intervention Type)

중재명칭(Intervention Name)

키워드(Keyword)

유효성결과(Recomendation)

연구비지원(Fund Source)

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참여저자수(Authors)

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DOI

KCD코드

ICD 03

건강보험코드

반복되는 천명을 주소로 내원한 3세 미만의 환아에서 25-hydroxyvitamin D의 혈청 내 농도와 관련된 인자 Factors associated with serum vitamin D levels in children with recurrent wheezing less than 3 years old

Abstract

키워드

반복되는 천명을 주소로 내원한 3세 미만의 환아에서 25-hydroxyvitamin D의 혈청 내 농도와 관련된 인자
Factors associated with serum vitamin D levels in children with recurrent wheezing less than 3 years old