KCTBASE

설문조사를 통한 국내 유전성 혈관부종 진료 현황 및 국내 사례 문헌고찰
Clinical experience in managing patients with hereditary angioedema in Korea: questionnaire survey and a literature review

Allergy Asthma & Respiratory Disease 2014년 2권 4호 p.277 ~ p.284

이서영(Lee Suh-Young) - 서울대학교 의과대학 내과학교실
강혜련(Kang Hye-Ryun) - 서울대학교 의과대학 내과학교실
정재우(Jung Jae-Woo) - 중앙대학교 의과대학 내과학교실
장광천(Jang Gwang-Cheon) - 국민건강보험공단 일산병원 소아청소년과
이수영(Lee Soo-Young) - 아주대학교 의과대학 소아청소년과학교실
안영민(Ahn Young-Min) - 을지대학교 의과대학 소아청소년과학교실
민경업(Min Kyung-Up) - 서울대학교 의과대학 내과학교실

Abstract

Purpose: Hereditary angioedema is a familial disease which is caused by a genetic deficiency or functional defect of the C1 inhibitor, and it features episodic swelling that can affect any part of the body. A great number of patients are estimated not to have an accurate diagnosis after the onset of symptoms, and close attention is required because sudden hereditary angioedema attacks can result in even death.

Methods: We sent an e-mail questionnaire to 975 members of the Korean Academy of Asthma, Allergy and Clinical Immunology. A total of 82 members replied. The questionnaire, including 15 questions about the diagnosis and management of hereditary angioedema, was developed by the anaphylaxis/urticaria, angioedema workgroup of the Korean Academy of Asthma, Allergy and Clinical Immunology.

Results: Forty-two percent of the respondents had experience with treatment of a suspected case of hereditary angioedema, and 15.9% made a confirmed diagnosis of hereditary angioedema. When the respondents suspected of cases, 91.4% of them performed tests for C3 and C4 concentrations and C1 inhibitor level. For maintenance treatment, most of the respondents used androgen, and only 22% found that C1 inhibitor concentrates can be prescribed through the Korea Orphan Drug Center in Korea.

Conclusion: Allergy physicians in Korea substantially recognized the correct diagnosis and treatment of hereditary angioedema. However, there was a lack of awareness for the latest treatments, such as C1 inhibitor concentrates. Education of doctors and the public is needed.

키워드

Hereditary angioedema, Questionnaires, Korea, disease management

KMID : 1035620140020040277

원문 및 링크아웃 정보

등재저널 정보

주제코드

주제명(Target field)

연구대상(Population)

연구참여(Sample size)

대상성별(Gender)

질병특성(Condition Category)

연구환경(Setting)

연구설계(Study Design)

연구기간(Period)

중재방법(Intervention Type)

중재명칭(Intervention Name)

키워드(Keyword)

유효성결과(Recomendation)

연구비지원(Fund Source)

근거수준평가(Evidence Hierarchy)

출판년도(Year)

참여저자수(Authors)

대표저자

DOI

KCD코드

ICD 03

건강보험코드

설문조사를 통한 국내 유전성 혈관부종 진료 현황 및 국내 사례 문헌고찰 Clinical experience in managing patients with hereditary angioedema in Korea: questionnaire survey and a literature review

Abstract

키워드

설문조사를 통한 국내 유전성 혈관부종 진료 현황 및 국내 사례 문헌고찰
Clinical experience in managing patients with hereditary angioedema in Korea: questionnaire survey and a literature review