Æ®¸®¸ÞÅäÇÁ¸²-¼³ÆĸÞÅå»çÁ¹ Å»°¨ÀÛ¿ä¹ýÀ¸·Î Ä¡·á¿¡ ¼º°øÇÑ Stenotrophomonas maltophilia °ñ¼ö¿° 1¿¹
Successful desensitization of trimethoprim-sulfamethoxazole in Stenostrophomonas maltophilia osteomyelitis
Allergy Asthma & Respiratory Disease 2014³â 2±Ç 3È£ p.218 ~ p.221
±è¼öÁ¤(Kim Soo-Jung) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÓ°æȯ(Lim Kyung-Hwan) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
°¹Î±Ô(Kang Min-Gyu) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹ÚÇѱâ(Park Han-Ki) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¶»óÇå(Cho Sang-Heon) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹Î°æ¾÷(Min Kyung-Up) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è¼¼ÈÆ(Kim Sae-Hoon) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀåÀ±¼®(Chang Yoon-Seok) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
Stenotrophomonas maltophilia is an emerging pathogen associated with morbidity and mortality in hospitalized patients. The treatment of S. maltophilia infection is challenging because clinical isolates are frequently resistant to most antimicrobial agents except trimethoprim-sulfamethoxazole (TMP-SMX). S. maltophilia osteomyelitis is a rare disease and requires a prolonged treatment with TMP-SMX. Here, we report an interesting case of a patient with S. maltophilia osteomyelitis who developed a delayed hypersensitivity reaction during TMP-SMX treatment and successfully treated after desensitization. TMP-SMX desensitization should be considered in patients with hypersensitivity to TMP-SMX, especially when there are no effective alternative drugs in S. maltophilia infection.
Å°¿öµå
Immunologic desensitization, Hypersensitivity, Trimethoprim-sulfamethoxazole combination, Stenotrophomonas maltophilia
KMID :
1035620140020030218
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