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Hypersensitivity reaction to aspirin accompanied by severe eosinophilia in a child with history of Kawasaki
Allergy Asthma & Respiratory Disease 2014³â 2±Ç 2È£ p.142 ~ p.145
¼³Àμ÷(Sol In-Suk) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
ÃÖ¸íÇö(Choi Myung-Hyun) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±è¹ÎÁ¤(Kim Min-Jung) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±èÀ±Èñ(Kim Yoon-Hee) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
ÀÌÈñ¼±(Lee Hee-Seon) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
ÇÑÀ±±â(Han Yoon-Ki) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±è±âȯ(Kim Ki-Hwan) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±è°æ¿ø(Kim Kyung-Won) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¼Õ¸íÇö(Sohn Myung-Hyun) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±è±Ô¾ð(Kim Kyu-Earn) - ¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
Abstract
Drug hypersensitivity is one of drug adverse reactions that develop in susceptible patients following exposure to certain drugs and cannot be predicted from the known pharmacology of a drug. Severe hypersensitivity is associated with high morbidity and mortality. Although the issue of hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) has been largely investigated in adults, data related to NSAIDs hypersensitivity is insufficient in childhood. And in spite of the recommendation to avoid use of aspirin due to Reye syndrome in children, aspirin is one of major treatment along with intravenous immunoglobulin in Kawasaki disease. We report a case of a 10-month-old boy who underwent intravenous immunoglobulin and aspirin treatment for Kawasaki disease, and subsequently revealed severe leukocytosis and eosinophilia. To our knowledge, there have been no previous reports of aspirin-induced eosinophilia in Korea.
Å°¿öµå
Eosinophilia, Drug hypersensitivity reaction, Aspirin, Kawasaki disease
KMID :
1035620140020020142
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