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±èÀÚ°æ(Kim Ja-Kyoung) - °¿ø´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ¼Ò¾Æ°úÇб³½Ç
±èÁøÅÃ(Kim Jin-Tack) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
¼µ¿ÀÎ(Suh Dong-In) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
°í¿µ·ü(Koh Young-Yull) - ¼¿ï´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
½ÅÀ±È£(Shin Youn-Ho) - Â÷ÀÇ°úÇдëÇб³ ¼Ò¾Æ°úÇб³½Ç
À̼ҿ¬(Lee So-Yeon) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ ÇѸ²´ëÇб³¼º½Éº´¿ø ¼Ò¾Æû¼Ò³â°ú
ÀÓ´ëÇö(Lim Dae-Hyun) - ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
Á¤ÁöÅÂ(Choung Ji-Tae) - °í·Á´ëÇб³ ÀÇ°ú´ëÇÐ ¼Ò¾Æ°úÇб³½Ç
±èÈ¿ºó(Kim Hyo-Bin) - ÀÎÁ¦´ëÇб³ ÀÇ°ú´ëÇÐ ÀÎÁ¦´ëÇб³»ó°è¹éº´¿ø ¼Ò¾Æû¼Ò³â°ú
Abstract
Asthma is not a homogeneous disease presenting variable clinical features, but a complex disorder consisting of many different disease entities characterized by variable air-flow limitation. To date, there are little effective preventive-strategies for the development of asthma, and it has been emphasized that early identification and intervention are the best ways to reduce the associated morbidities, quality of life, and socioeconomic burden. Predicting the natural course of asthma is still difficult, although various phenotypic approaches and predictive scores are developed and widely used. The present phenotypes and predictive scores may be reliable in the population, but those appear to be unreliable in each individual in real practice. Either undertreatment or overtreatment in childhood asthma is an important issue, because they are associated with poor compliance, increments of socioeconomic burdens, and poor quality of life. There is no doubt about the clinical efficacy of inhaled corticosteroid (ICS) in childhood asthma, but the negative effect of long-term use of ICS on the height is emerging. Therefore general physicians should consider an individualized management using specific phenotypes and endotypes, and regularly re-evaluate the drug-response, level of control, and adherence/compliance to avoid inadequate treatment.
Å°¿öµå
Phenotype, Endotype, Asthma, Child
KMID :
1035620140020020085
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