ÀåÀº¹Ì(Chang Eun-Mi) - CHA University Fertility Center of CHA Gangnam Medical Center Department of Obstetrics and Gynecology
(Song Hang-Seok) - CHA University College of Life Science Department of Biomedical Science
À̵¿·ü(Lee Dong-Ryul) - CHA University College of Life Science Department of Biomedical Science
ÀÌ¿ì½Ä(Lee Woo-Sik) - CHA University Fertility Center of CHA Gangnam Medical Center Department of Obstetrics and Gynecology
À±Å±â(Yoon Tae-Ki) - CHA University CHA Gangnam Medical Center Fertility Center
Abstract
IVM refers to the maturation of immature oocytes in culture after their recovery from small antral follicles at the stage prior to selection and dominance. IVM requires little or no FSH in vivo and has been proposed as an alternative to conventional IVF, since it reduces the primary adverse effects caused by controlled ovarian stimulation, including the ovarian hyperstimulation syndrome. Moreover, IVM is a promising option for cases for which no standard protocol is suitable, such as FSH resistance, contraindications for ovarian stimulatory drugs, and the need for urgent fertility preservation. Recently, IVM has been used in women with regular cycles and normal ovaries. However, the pregnancy rate following IVM is suboptimal compared with that of conventional IVF, indicating that further studies to optimize the protocol and the culture conditions are warranted.
Å°¿öµå
Fertility preservation, Follicle culture, Infertility, In vitro maturation, Oocyte
KMID :
1033620140410020041
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