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Radiation Induced Peripheral Arterial Disease associated with Diabetes which Initially Considered as Diabetic Foot Disease
Journal of Korean Diabetes 2014³â 15±Ç 2È£ p.124 ~ p.128
ÀÌ¿øÇü(Lee Weon-Hyoung) - °í½Å´ëÇб³ Àǰú´ëÇÐ º¹À½º´¿ø ³»ºÐºñ´ë»ç³»°ú
ÇãÀçÁØ(Heo Jae-Joon) - °í½Å´ëÇб³ Àǰú´ëÇÐ º¹À½º´¿ø ³»ºÐºñ´ë»ç³»°ú
¿©°íÀº(Yeo Go-Eun) - °í½Å´ëÇб³ Àǰú´ëÇÐ º¹À½º´¿ø ³»ºÐºñ´ë»ç³»°ú
ÃÖ¿µ½Ä(Choi Young-Sik) - °í½Å´ëÇб³ Àǰú´ëÇÐ º¹À½º´¿ø ³»ºÐºñ´ë»ç³»°ú
¹Ú¿äÇÑ(Park Yo-Han) - °í½Å´ëÇб³ Àǰú´ëÇÐ º¹À½º´¿ø ³»ºÐºñ´ë»ç³»°ú
±Ç¼ö°æ(Kwon Su-Kyoung) - °í½Å´ëÇб³ Àǰú´ëÇÐ º¹À½º´¿ø ³»ºÐºñ´ë»ç³»°ú
Abstract
Therapeutic high-dose radiation can induce atherosclerotic changes of affected arteries. Radiation-associated atherosclerotic diseases of coronary, carotid and subclavian arteries have been demonstrated for years in cancer survivors, but peripheral arterial disease (PAD) associated with radiation is rarely reported. PAD is one of the major
macrovascular complications of diabetes and is associated with morbidity and increased mortality. We experienced
a case of PAD associated with radiation therapy in a 65-year-old diabetic female patient who had undergone cervical cancer treatment 19 years prior. Computed tomographic angiogram showed occlusion and stenosis from common iliac arteries to superficial femoral arteries. However, both infrapopliteal arteries that are commonly involved in diabetes associated PAD were preserved. She was successfully treated with percutaneous angioplasty combined with femoro-femoral bypass operation. Based on the extent and severity of arterial stenosis in this nonsmoking diabetic woman who had a history of high-dose radiation to her pelvis, we concluded that atherosclerotic lesions in this patient were caused by high-dose pelvic irradiation and then exacerbated by diabetes. Therefore, special attention should be given to diabetic patients with history of pelvic irradiation with regard to development of atherosclerosis of peripheral arteries, especially in the pelvic area.
Ű¿öµå
Peripheral arterial disease, Diabetes mellitus, Radiation, Diabetic foot
KMID :
1030220140150020124
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