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Sleep Disorders in Neurodegenerative Disorders
¼ö¸é 2014³â 11±Ç 1È£ p.1 ~ p.4
¼Á¾±Ù(Seo Jong-Geun) - °æºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
¹Ú¼ºÆÄ(Park Sung-Pa) - °æºÏ´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ½Å°æ°úÇб³½Ç
ÀÌÈ£¿ø(Lee Ho-Won) - °æºÏ´ëÇб³ ³ú°úÇבּ¸¼Ò
Abstract
Neurodegenerative diseases result from deterioration of neurons which may eventually lead to central nervous system-related dysfunction including sleep disorders. The pathogenesis of these disturbances may be secondary to direct structural alterations of the sleep-wake generating cells and networks or be the consequence of several indirect mechanisms. The most frequent sleep disturbances in patients with neurodegenerative diseases are insomnia, hypersomnia, parasomnias, excessive nocturnal motor activity, circadian sleep-wake rhythm disturbances, and respiratory dysrhythmias. Here, we classify the neurodegenerative diseases, taking into consideration the type of molecular neurodegeneration as synucleinopathies and tauopathies and reviewed sleep disorders observed in each degeneration type. The aim of this review is to provide data on sleep disturbances in two categories of neurodegenerative disorders.
Ű¿öµå
Neurodegenerative diseases, Sleep disorders, Parkinsonism, Dementia
KMID :
1002120140110010001
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