Á¤¹ÎÈ£(Jung Min-Ho) - Chonnam National University Hwasun Hospital Department of Neurosurgery
¹®°æ¼·(Moon Kyung-Sub) - Chonnam National University Hwasun Hospital Department of Neurosurgery
ÀÌ°æÈ(Lee Kyung-Hwa) - Chonnam National University Hwasun Hospital Department of Pathology
Àå¿ì¿(Jang Woo-Youl) - Chonnam National University Hwasun Hospital Department of Neurosurgery
Á¤Å¿µ(Jung Tae-Young) - Chonnam National University Hwasun Hospital Department of Neurosurgery
Á¤½Å(Jung Shin) - Chonnam National University Hwasun Hospital Department of Neurosurgery
Abstract
Objective: Based on surgical outcomes of patients with infratentorial meningiomas surgically treated at our institution, we analyzed the predictors for surgical resection, recurrence, complication, and survival.
Methods: Of surgically treated 782 patients with intracranial meningioma, 158 (20.2%) consecutive cases of infratentorial location operated on between April 1993 and May 2013 at out institute were reviewed retrospectively. The patients had a median age of 57.1 years (range, 16--77 years), a female predominance of 79.7%, and a mean follow-up duration of 48.4 months (range, 0.8--242.2 months).
Results: Gross total resection (Simpson¡¯s grade I & II) was achieved in 81.6% (129/158) of patients. Non-skull base location was an independent factor for complete resection. The recurrence rate was 13.3% (21/158) and the 5-, 10-, and 15-year recurrence rates were 8.2%, 12.0%, and 13.3%, respectively. Benign pathology, postoperative KPS over than 90, low peritumoral edema, and complete resection were significantly associated with longer recurrence-free survival rate. The 5-, 10-, and 15-year survival rates were 96.2%, 94.9%, and 94.9%, respectively. Benign pathology, postoperative KPS over than 90 and complete resection were significantly associated with a longer survival rate. The permanent complication rate was 13% (21/158). Skull base location and postoperative KPS less than 90 were independent factors for the occurrence of permanent complication.
Conclusion: Our experience shows that infratentorial meningiomas represent a continuing challenge for contemporary neurosurgeons. Various factors are related with resection degree, complications, recurrence and survival.
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Complication, Intracranial meningioma, Infratentorial, Recurrence, Surgical outcome, Survival
KMID :
1001920140550060321
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