Solitary Cavernous Sinus Neurosarcoidosis Mimicking Neurosyphilis

Journal of Korean Neurosurgical Society 2014³â 55±Ç 1È£ p.61 ~ p.63

±èµ¿ÇÏ(Kim Dong-Ha) - Pusan National University School of Medicine Pusan National University Hospital Department of Neurosurgery
Àú¿øÈ£(Cho Won-Ho) - Pusan National University School of Medicine Pusan National University Hospital Department of Neurosurgery
Á¶±Ô¼·(Cho Kyu-Sup) - Pusan National University School of Medicine Pusan National University Hospital Department of Otolaryngology
(Cha Seong-Heon) - Pusan National University School of Medicine Pusan National University Hospital Department of Neurosurgery

Abstract

A differential diagnosis between neurosarcoidosis and neurosyphilis is particularly problematic in patients with a positive serologic result for syphilis. We report here a patient with a solitary cavernous sinus sarcoidosis who had a history of syphilis and showed rapidly progressing cavernous sinus syndrome. A transsphenoidal biopsy was performed and a histopathologic examination revealed a non-caseating granuloma with an asteroid body. His facial pain disappeared after steroid therapy. He received oral prednisolone for one year. A follow-up magnetic resonance imaging of the brain revealed resolution of the mass over the cavernous sinus. Particularly in patients with a history of syphilis, neurosyphilis should be included in a differential diagnosis of neurosarcoidosis.

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Neurosarcoidosis, Neurosyphilis, Sarcoidosis, Cavernous sinus
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