Collapsed L4 Vertebral Body Caused by Brucellosis

Journal of Korean Neurosurgical Society 2014³â 55±Ç 1È£ p.48 ~ p.50

(Ekici Mehmet Ali) - Sevket Y©¥lmaz Training and Research Hospital Department of Neurosurgery
(Ozbek Zuhtu) - Yunus Emre State Hospital Department of Neurosurgery
(Kazanc©¥ Burak) - Sevket Y©¥lmaz Training and Research Hospital Department of Neurosurgery
(Guclu Bulent) - Sevket Y©¥lmaz Training and Research Hospital Department of Neurosurgery

Abstract

Brucellosis is caused by gram-negative, aerobic, non-motile, facultative, intracellular coccobacilli belonging to the genus Brucella. A 50-year-old man working as an employee was admitted to neurosurgery clinic with severe low back, radicular right leg pain and hypoesthesia in right L4-5 dermatomes for 2 months. Brucella tube agglutination (Wright) test was positive in serum sample of the patient with a titer of 1/640. Brucella melitensis was isolated from blood culture. X-ray and MRI of the lomber spine showed massive collapse of L4 vertebral body. Neural tissue was decompressed and then posterior L3-5 short segment transpedicular screw fixation and stabilization was performed. Brucella melitensis was isolated from microbiologic culture of pathologic specimen. Antibiotic therapy was given as doxycycline 200 mg/day and rifampicin 600 mg/day for 6 months. Brucellosis is a systemic zoonotic infection and still an important public health problem in many geographical parts of the world. Vertebral body collapse caused by brucellosis occurs very rarely but represents a neurosurgical emergency because of its potential for causing rapidly progressive spinal cord compression and permanent paralysis. Neurosurgeons, emergency department personnel as well as infectious disease specialists should always keep a high index of suspicion and include brucellosis in the differential diagnosis of vertebral body collapse.

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Brucellosis, Spinal infections, Treatment, Vertebral collapse
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