A Case of Localized Amyloid Light-Chain Amyloidosis in the Small Intestine
Intestinal Research 2014³â 12±Ç 3È£ p.245 ~ p.250
ÃÖÁ¾È¿(Choi Jong-Hyo) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
°íºÀ¹Î(Ko Bong-Min) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
(Kim Cheol) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
±èÈñ°æ(Kim Hee-Kyung) - Soonchunhyang University College of Medicine Department of Pathology
ÇÑÀçÇÊ(Han Jae-Pil) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
È«¼öÁø(Hong Su-Jin) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
¹®Á¾È£(Moon Jong-Ho) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
À̹®¼º(Lee Moon-Sung) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
Abstract
Amyloidosis is characterized by the abnormal deposition of extracellular amyloid fibrils. Cases involving amyloid light-chain amyloidosis in the small intestine have been reported infrequently in Korea. Here, we report a case of localized light chain protein amyloidosis in the small intestine. Esophagogastroduodenoscopy, push enteroscopy, and capsule endoscopy revealed submucosal tumor-like lesions, multiple shallow ulcers, and several erosions in the distal duodenum and jejunum. An endoscopic biopsy established the diagnosis of amyloidosis. In through an immunohistochemical analysis, the presence of lambda light chain protein was detected. The patient had no evidence of an underlying clonal plasma cell disorder or additional organ involvement. Therefore, we concluded that the patient had localized amyloidosis of the small intestine. (Intest Res 2014;12:245-250)
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Amyloidosis, Intestine, small, Endosonography, Enteroscopy, Capsule endoscopy
KMID :
0988920140120030245
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À¯È¿¼º°á°ú(Recomendation)
This study concluded that the patient had localized amyloidosis of the small intestine