¼ÒÀå ÃâÇ÷ÀÌ ÀÇ½ÉµÈ ¹®¸Æ¾Ð Ç×ÁøÁõ ȯÀÚÀÇ Ä¸½¶³»½Ã°æ °Ë»ç
Capsule Endoscopy for Suspected Small Bowel Bleeding in Patients with Portal Hypertension

Intestinal Research 2011³â 9±Ç 2È£ p.129 ~ p.138

õ°­ÀÏ(Cheon Kang-Il) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±èÁø¿À(Kim Jin-Oh) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
È«¼º¿í(Hong Sung-Wook) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
Àü¼º¶õ(Jeon Seong-Ran) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌÅÂÈñ(Lee Tae-Hee) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
±èÇö°Ç(Kim Hyun-Gun) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
Á¶¿ø¿µ(Cho Won-Young) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
±è¿ÏÁß(Kim Wan-Jung) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è¹ÎÁ¤(Kim Min-Jeong) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
Á¤½Â¿ø(Jung Seung-Won) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀåÀ翵(Jang Jae-Young) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
°íºÀ¹Î(Ko Bong-Min) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
Á¶ÁÖ¿µ(Cho Joo-Young) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò
ÀÌÁؼº(Lee Joon-Seong) - ¼øõÇâ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç, ¼ÒÈ­±â¿¬±¸¼Ò

Abstract

¸ñÀû :¹®¸Æ¾Ð Ç×ÁøÁõÀÌ Àִ ȯÀÚÀÇ ¼ÒÀå ÃâÇ÷¿¡ ´ëÇÑ ±¹³» ¿¬±¸´Â ¾ÆÁ÷ ¹Ì¹ÌÇÑ ½ÇÁ¤ÀÌ´Ù. À̹ø ¿¬±¸´Â ¼ÒÀå ÃâÇ÷ÀÌ ÀÇ½ÉµÈ ¹®¸Æ¾Ð Ç×ÁøÁõ ȯÀÚ¸¦ ´ë»óÀ¸·Î ĸ½¶³»½Ã°æ °Ë»ç °æÇèÀ» º¸°íÇÏ°íÀÚ ÇÑ´Ù.

´ë»ó ¹× ¹æ¹ý :º» ¼¾ÅÍ¿¡¼­ 2003³â 7¿ùºÎÅÍ 2010³â 6¿ù±îÁö ¼ÒÀåÁúȯÀÌ ÀÇ½ÉµÈ 501¿¹¸¦ ´ë»óÀ¸·Î ĸ½¶³»½Ã°æ °Ë»ç¸¦ ÇÏ¿´´Ù. 501¿¹ Áß¿¡¼­ ¼ÒÀå ÃâÇ÷ÀÌ ÀÇ½ÉµÈ °£°æº¯ÁõÀ¸·Î ÀÎÇÑ ¹®¸Æ¾Ð Ç×ÁøÁõ ȯÀÚ 9¸íÀ» ´ë»óÀ¸·Î ÈÄÇ⠺м®ÇÏ¿´´Ù.

°á°ú :³²ÀÚ´Â 6¸íÀ̾ú°í, Æò±Õ ¿¬·ÉÀº 53.4¼¼À̾ú´Ù. Æò±Õ Ç÷»ö¼Ò ¼öÄ¡´Â 8.1 g/dL¿´´Ù. ĸ½¶³»½Ã°æ¿¡¼­ ¹®¸Æ¾ÐÇ×Áø ¼ÒÀ庴Áõ 9¿¹(100%), °øÀå Á¤¸Æ·ù 4¿¹(44.4%), °øÀå ¹× È¸ÀåÀÇ Ç÷°ü ÀÌÇü¼º 5¿¹(55.5%), ´Ù¹ß¼º ¼ÒÀå ¹Ì¶õ 1¿¹(11.1%), °øÀå Á¡¸·ÀÇ °ú¸³Çü º¯È­ 1¿¹(11.1%), ¼ÒÀå Á¡¸· È«¹Ý 3¿¹(33.3%)°¡ °üÂûµÇ¾ú´Ù. °øÀå Á¤¸Æ·ùÀÇ È°µ¿¼º ÃâÇ÷Àº 2¿¹(22.2%)¿¡¼­ °üÂûµÇ¾ú´Ù. ĸ½¶³»½Ã°æ¿¡¼­ È°µ¿¼º ÃâÇ÷Àº ¾ø¾úÀ¸³ª 4¿¹(44.4%)´Â ¹®¸Æ¾ÐÇ×Áø ¼ÒÀ庴ÁõÀ» ÃâÇ÷º´¼Ò·Î Áø´ÜÇÏ¿´´Ù.

°á·Ð :¹®¸Æ¾ÐÇ×Áø ¼ÒÀ庴ÁõÀÇ Áø´Ü°ú ÃâÇ÷ º´¼Ò¸¦ ±Ô¸íÇÏ´Â µ¥ ĸ½¶³»½Ã°æÀº ¸Å¿ì À¯¿ëÇÑ °Ë»çÀÌ´Ù. ÇâÈÄ ÀüÇâÀû ´Ù±â°ü ĸ½¶³»½Ã°æ ¿¬±¸¸¦ ÅëÇØ ¹®¸Æ¾ÐÇ×Áø ¼ÒÀ庴ÁõÀÇ À¯º´·ü ¹× ÀÓ»ó ÀÇÀǸ¦ ±Ô¸íÇØ¾ß ÇÒ °ÍÀÌ´Ù.
Background/Aims :In Korea, limited data are available on small bowel bleeding in patients with portal hypertension. This study reports on the use of capsule endoscopy in cases of suspected small bowel bleeding in patients with portal hypertension.

Methods:Capsule endoscopy was used at our hospital to evaluate small bowel disease in 501 cases from July 2003 to June 2010. Of those cases, nine patients with portal hypertension due to liver cirrhosis with suspected small bowel bleeding were selected for the study. A retrospective analysis was performed using data from medical records.

Results:Six of the nine (66.7%) patients were males with an average age of 53.4 years. The average hemoglobin level was 8.1 g/dL. Abnormalities noted during capsule endoscopy included portal hypertensive enteropathy in all nine cases (100%), jejunal varices in four (44.4%), jejunal and ileal angiodysplasia in five (55.5%), multiple small bowel erosions in one (11.1%), granularity of the jejunal mucosa in one (11.1%), and small bowel erythema in three (33.3%). Active bleeding from jejunal varices was detected in two patients (22.2%). Despite having no obvious active bleeding during the capsule endoscopy, four patients (44.4%) were diagnosed with portal hypertensive enteropathy with obscure small bowel bleeding.

Conclusions:Capsule endoscopy is a useful diagnostic tool for the evaluation of small bowel bleeding in patients with portal hypertensive enteropathy. Additional prospective and multicenter studies on the use of capsule endoscopy are needed to evaluate the incidence and clinical importance of portal hypertensive enteropathy.

Å°¿öµå

ĸ½¶³»½Ã°æ, °£°æº¯Áõ, ¼ÒÀå ÃâÇ÷, ¹®¸Æ¾ÐÇ×Áø ¼ÒÀ庴Áõ
Capsule Endoscopy, Liver Cirrhosis, Small Bowel Bleeding, Portal Hypertensive Enteropathy
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
ÇмúÁøÈïÀç´Ü(KCI) KoreaMed ´ëÇÑÀÇÇÐȸ ȸ¿ø 
ÁÖÁ¦ÄÚµå
ÁÖÁ¦¸í(Target field)
¿¬±¸´ë»ó(Population)
¿¬±¸Âü¿©(Sample size)
´ë»ó¼ºº°(Gender)
Áúº´Æ¯¼º(Condition Category)
¿¬±¸È¯°æ(Setting)
¿¬±¸¼³°è(Study Design)
¿¬±¸±â°£(Period)
ÁßÀç¹æ¹ý(Intervention Type)
ÁßÀç¸íĪ(Intervention Name)
Å°¿öµå(Keyword)
À¯È¿¼º°á°ú(Recomendation)
Capsule endoscopy was done for patients with small bowel bleeding and portal hypertension and it was a useful diagnostic tool for the evaluation of small bowel bleeding in patients with portal hypertensive enteropathy.
¿¬±¸ºñÁö¿ø(Fund Source)
±Ù°Å¼öÁØÆò°¡(Evidence Hierarchy)
ÃâÆdz⵵(Year)
Âü¿©ÀúÀÚ¼ö(Authors)
´ëÇ¥ÀúÀÚ
DOI
KCDÄÚµå
ICD 03
°Ç°­º¸ÇèÄÚµå