강현욱(Kang Hyun-Wook) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
박찬우(Park Chan-Woo) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
김우진(Kim Woo-Jin) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
송상윤(Song Sang-Yun) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
나국주(Na Kook-Joo) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
정재욱(Jeong Jae-Uk) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
윤미선(Yoon Mee-Sun) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
안성자(Ahn Sung-Ja) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
최유덕(Choi Yoo-Duk) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
(Choi Chan) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
이다운(Lee Da-Un) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
선현주(Seon Hyun-Ju) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
김윤현(Kim Yun-Hyeon) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
권성영(Kwon Seong-Young) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
범희승(Bom Hee-Seung) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
오인재(Oh In-Jae) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
김규식(Kim Kyu-Sik) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
김영철(Kim Young-Chul) - Chonnam National University Hwasun Hospital Lung and Esophageal Cancer Clinic
Abstract
Purpose: Lung cancer has been the leading cause of death in South Korea since the year 2000. Adenocarcinoma became the most frequent type in the national survey of lung cancer since year 2005.
Materials and Methods: We analyzed 5,456 cases with lung cancer from 2004 to 2012 in a community cancer center. The mean age was 69.9 years, and 78.9% was male.
Results: Adenocarcinoma (ADC, 40.8%) was the most frequent type, followed by squamous cell carcinoma (SQC, 36.4%), small cell carcinoma (SCC, 14.8%) and non-small cell lung cancer (NSCLC) not otherwise specified (8.1%). In male patients, SQC was the most frequent type (43.5%), while ADC showed highest incidence in females (72.6%). Anatomic stage at diagnosis in NSCLC was I (10.3%), II (5.8%), IIIA (15.7%), IIIB (19.2%), and IV (49.0%). In SCC, 41.7% was in limited stage and 58.3% was diagnosed in extensive stage. The proportion of never smoker has been increased from 19.1% in 2004∼2008 to 25.4% in 2009∼2012. Never-smokers are more likely to be female (68.2% vs. 4.0%, p<0.001), have ADC (69.9% vs. 31.3%, p<0.001), and manifest as stage IV disease (58.5% vs. 45.2%, p<0.001), compared to smokers. Among 1,908 cases whose initial treatment was recorded, 42.5% received chemotherapy, 25.7% received radiation treatment, 20.5% received surgery and the remaining 11.3% received supportive cares only or transferred to other health care facilities.
Conclusion: In conclusion, proportion of lung cancer in never-smoker is increasing. As screening for smokers will miss this growing population, we need to discover biomarkers to find high risk population of lung cancer.
키워드
Lung neoplasms, Epidemiology, Smoking, Female
KMID :
0982820120110020089
원문 및 링크아웃 정보
등재저널 정보
유효성결과(Recomendation)
The proportion of never smoker has been increased from 19.1% in 2004∼2008 to 25.4% in 2009∼2012. Never-smokers are more likely to be female have Adenocarcinoma. Among 1,908 cases whose initial treatment was recorded, 42.5% received chemotherapy, 25.7% received radiation treatment, 20.5% received surgery and the remaining 11.3% received supportive cares only or transferred to other health care facilities.