Tumor Lysis Syndrome Induced by Radiotherapy in Non- Small Cell Lung Cancer

Journal of Lung Cancer 2010³â 9±Ç 2È£ p.106 ~ p.109

³ëµ¿È¿(Noh Dong-Hyo) - Wonkwang University College of Medicine Department of Internal Medicine
Ȳ±âÀº(Hwang Ki-Eun) - Wonkwang University College of Medicine Department of Internal Medicine
½ÅÁ¤Çö(Shin Jeong-Hyun) - Wonkwang University College of Medicine Department of Internal Medicine
±èµ¿(Kim Dong) - Wonkwang University College of Medicine Department of Internal Medicine
Á¶°æÈ­(Cho Kyung-Hwa) - Wonkwang University College of Medicine Department of Internal Medicine
Á¤ÀºÅÃ(Jeong Eun-Taik) - Wonkwang University College of Medicine Department of Internal Medicine
±èÇзÄ(Kim Hak-Ryul) - Wonkwang University College of Medicine Department of Internal Medicine
ÃÖ±ÝÇÏ(Choi Keum-Ha) - Wonkwang University College of Medicine Department of Pathology
¹Ú¼ºÈÆ(Park Seong-Hoon) - Wonkwang University School of Medicine Department of Radiology

Abstract

Tumor lysis syndrome (TLS) is an oncologic emergency that is characterized by numerous metabolic abnormalities, including hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia and increased serum creatinine. This syndrome is common for tumors with rapid cell turnover and growth rates, and for bulky tumors with high sensitivity to anti-neoplastic treatments. Hence, TLS is a well-recognized clinical problem in hematologic malignancies. TLS is rarely observed to be induced in solid tumors by chemotherapy. Herein we present the second case of TLS that developed during radiotherapy in a patient with non-small cell lung cancer.

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Tumor lysis syndrome, Radiotherapy, Non-small cell lung carcinoma
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Radiotherapy caused the decrease in urine volume and the lab findings of Tumor lysis syndrome (TLS).
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DOI
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ICD 03
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