A Case of Pneumatosis Intestinalis Induced by Chemotherapy in a Patient with Lung Cancer

Journal of Lung Cancer 2008³â 7±Ç 2È£ p.101 ~ p.102

±Ç¹ÌÇý(Kwon Mi-Hye) - °Ç¾ç´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±Ç¼±Áß(Kwon Sun-Jung) - °Ç¾ç´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÃÖÀ¯Áø(Choi Eu-Gene) - °Ç¾ç´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
³ª¹®ÁØ(Na Moon-Jun) - °Ç¾ç´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¼ÕÁö¿õ(Son Ji-Woong) - °Ç¾ç´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç

Abstract

Pneumatosis intestinalis is an uncommon condition that is characterized by the presence of gas within the bowel wall. We experienced a case of pneumatosis intestinalis after cession of chemotherapy and we herein report on this case. A 58-year old man was admitted to our hospital for the evaluation of incidentally recognized pneumatosis intestinalis. He was diagnosed as having non small cell lung cancer in August 2006 and he received radiation therapy for concomitant brain metastasis and SVC syndrome in September 2006. He achieved a partial response after completing 6 cycles of chemotherapy with gemcitabine and cisplatin. Newly enlarged lymph nodes were observed on the follow-up CT, and chemotherapy with paclitaxel and carboplatin was started in July 2007. Due to the lack of a response, the therapeutic regimen was switched to oral erlotinib. After 1 month of treatment, the follow-up CT for response evaluation revealed pneumatosis intestinalis in the ascending colon without any subjective symptoms such as fever or abdominal pain. The laboratory results were within the normal range except for a slight increase of leukocytes. He underwent right hemicolectomy, but he didn¡¯t survive his postoperative acute renal failure and pneumonia.

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Pneumatosis intestinalis, Chemotherapy, Non small cell lung cancer
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He didn¡¯t survive his postoperative acute renal failure and pneumonia after several chemotherapeutic treatments.
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DOI
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