(Choi Sung-S) - Chung-Ang University College of Medicine Medical Research Institute
ÀÌ»ó·¡(Lee Sang-Rae) - Korea Research Institute of Bioscience and Biotechnology National Primate Research Center
±è¼ºÀ¯(Kim Seung-U) - University of British Columbia Department of Medicine
ÀÌÈ«ÁØ(Lee Hong-Jun) - Chung-Ang University College of Medicine Medical Research Institute
Abstract
The loss of neuronal cells in the central nervous system may occur in many neurodegenerative diseases. Alzheimer¡¯s disease is a common senile disease in people over 65 years, and it causes impairment characterized by the decline of mental function, including memory loss and cognitive impairment, and affects the quality of life of patients. However, the current therapeutic strategies against AD are only to relieve symptoms, but not to cure it. Because there are only a few therapeutic strategies against Alzheimer¡¯s disease, we need to understand the pathogenesis of this disease. Cell therapy may be a powerful tool for the treatment of Alzheimer¡¯s disease. This review will discuss the characteristics of Alzheimer¡¯s disease and various available therapeutic strategies.
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Alzheimer¡¯s disease, stem cell-gene therapy, transplantation
KMID :
0892920140230010045
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