Clopidogrel Åõ¿© ÈÄ ¹ß»ýÇÑ Ç÷Àü¼º Ç÷¼ÒÆÇ°¨¼Ò¼º ÀÚ¹ÝÁõ 1¿¹
A Case of Thrombotic Thrombocytopenic Purpura associated with Clopidogrel in a Patient with Acute Cerebral Infarction
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¹ÚÁøÈñ(Park Jin-Hee) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌ¿µº¹(Lee Yeong-Bok) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹ÚÇÏ´Ã(Park Ha-Neul) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹ÎÁö¿ø(Min Ji-Won) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
°íÀ¯¹Ì(Ko Yu-Mi) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è¿µ¿Á(Kim Young-Ok) - °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
º» Áõ·Ê´Â ±Þ¼º ³ú°æ»ö ȯÀÚ¿¡¼ clopidgrel º¹¿ë ÈÄ ¹ß»ýÇÑ Ç÷Àü¼º Ç÷¼ÒÆÇ °¨¼Ò¼º ÀÚ¹ÝÁõÀÇ ¿¹ÀÌ´Ù. ȯÀÚ´Â ±Þ¼º ³ú°æ»öÀ¸·Î Ÿ º´¿ø¿¡¼ ÀÔ¿øÄ¡·á Áß 10º´ÀÏ°ºÎÅÍ ¹ß»ýÇÑ ¹ß¿ ¹× Ç÷¼ÒÆÇ°¨¼Ò¸¦ ÁÖ¼Ò·Î ³»¿øÇÏ¿© Ç÷Àü¼º Ç÷¼ÒÆÇ °¨¼Ò¼º ÀÚ¹ÝÁõÀ¸·Î Áø´Ü¹Þ°í Ç÷Àå ±³È¯¼ú Ä¡·á¸¦ ½ÃÇà¹Þ¾Ò´Ù. Clopidogrel º¹¿ë ÈÄ ¹ß»ýÇÏ´Â TTP´Â ¹ß»ýºóµµ´Â ³·À¸³ª Á¶±â¿¡ ¹ß°ßÇÏ¿© Ä¡·áÇÏÁö ¾ÊÀ¸¸é ÁøÇà°úÁ¤ÀÌ ±Þ¼Óµµ·Î ÁøÇàÇÏ¿© »ç¸Á¿¡ À̸£´Â ¸Å¿ì Ä¡¸íÀûÀÎ ÁúȯÀ¸·Î ¹ß»ý°¡´É¼ºÀ» ¹Ýµå½Ã ÀÎÁöÇÏ°í ÀÖ¾î¾ß ÇÒ °ÍÀ¸·Î »ý°¢µÈ´Ù.
Clopidogrel is an antiplatelet agent prescribed widely to prevent stent thrombosis after coronary or peripheral vascular interventions and for stroke prophylaxis. The side effects of this drug include gastrointestinal symptoms, such as nausea, abdominal pain, vomiting, and bleeding. Thrombotic thrombocytopenia purpura (TTP) is a rare complication of this drug. Here, we report a case of clopidogrel-associated TTP in a patient with cerebral infarction. To our knowledge, it is first reported case of clopidogrel- associated TTP in Korea.
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Ç÷Àü¼º Ç÷¼ÒÆÇ °¨¼Ò¼º ÀÚ¹ÝÁõ, Clopidogrel
Thrombotic thrombocytopenic purpura, Clopidogrel
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