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A Case of Pulmonary Tumor Thrombotic Microangiopathy in a Patient with Advanced Gastric Cancer
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ÀüÁöÀº(Jun Ji-Eun) - ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±èÁ¤ÈÆ(Kim Jung-Hoon) - ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
À¯´öÇö(Ryu Duck-Hyun) - ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌÁöÀº(Lee Ji-Eun) - ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¤È£Áß(Jeong Ho-Jung) - ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¾çÁ¤ÈÆ(Yang Jeong-Hoon) - ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
Æóµ¿¸Æ Á¾¾ç Ç÷Àü¼º ¹Ì¼¼Ç÷°üº´ÁõÀº Æóµ¿¸Æ °íÇ÷¾ÐÀ» À¯¹ßÇÏ°í ¿ì½ÉºÎÀüÀ¸·Î ÁøÇàÇÏ¿© »ç¸Á¿¡ À̸¦ ¼ö ÀÖ´Â ¾Ï°ú °ü·ÃµÈ È£Èí±â°è ÇÕº´ÁõÀÌ´Ù. Áø´ÜÀ» À§ÇÑ ¿µ»óÇÐÀû °Ë»çµéÀÌ ÀÖÁö¸¸ ¹Î°¨µµ¿Í ƯÀ̵µ°¡ ³·°í, Áø´Ü Àü ±Þ¼ÓÈ÷ ¾ÇÈµÇ¾î »ç¸ÁÇϹǷΠºÎ°ËÀ¸·Î È®ÀÎÇÏ´Â °æ¿ì°¡ ´ëºÎºÐÀÌ´Ù. ÀúÀÚµéÀº À§¾ÏÁ¾À» Áø´Ü¹Þ°í À§ÀüÀýÁ¦¼ú ¹× º¸Á¶ Ç×¾Ï ÈÇÐ ¹æ»ç¼± Ä¡·á ÈÄ Àç¹ß ¾øÀÌ °æ°ú °üÂûÇÏ´Ù°¡ ±Þ¼ÓÈ÷ ¾ÇȵǴ ¿îµ¿¼º È£Èí°ï¶õÀ» ÁÖ¼Ò·Î ³»¿øÇÑ È¯ÀÚ¿¡°Ô¼ Æó Á¶Á÷ °Ë»ç·Î Áø´ÜµÈ Æóµ¿¸Æ Á¾¾ç Ç÷Àü¼º ¹Ì¼¼Ç÷°üº´ÁõÀ» °æÇèÇÏ
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Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare and fatal cancer-related pulmonary complication leading to severe pulmonary hypertension, right heart failure, and death. Few cases of PTTM have been diagnosed antemortem. A 62-year-old male showing complete remission of gastric cancer presented with exertional dyspnea. Transthoracic echocardiography showed marked dilation of the right atrium, right ventricle, and the small left ventricle with normal left ventricular function. Right heart catheterization also showed mild to moderate pulmonary hypertension. A chest computed tomography scan revealed no evidence of acute pulmonary thromboembolism, but it showed consolidations with subpleural nodules in both lower lobes, and a lung perfusion scan showed multifocal, non-segmental perfusion defects. Finally, a diagnostic lung biopsy with video-assisted thoracoscopic surgery was performed, and the pathologic findings were compatible with PTTM. Here, we report a case of gastric cancer-related PTTM that was diagnosed antemortem.
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Æóµ¿¸Æ Á¾¾ç Ç÷Àü¼º ¹Ì¼¼Ç÷°üº´Áõ, Æóµ¿¸Æ °íÇ÷¾Ð, À§¾ÏÁ¾
Pulmonary tumor thrombotic microangiopathy, Pulmonary hypertension, Gastric cancer
KMID :
0882420140870050593
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