ÀÚ°¡Á¶Ç÷¸ð¼¼Æ÷ ÀÌ½Ä ÈÄ ¹ß»ýÇÑ È£ÁöŲ¸²ÇÁÁ¾
Hodgkin¡¯s Lymphoma after Autologous Hematopoietic Stem Cell Transplantation for Angioimmunoblastic T-cell Lymphoma
´ëÇѳ»°úÇÐȸÁö 2014³â 86±Ç 6È£ p.774 ~ p.780
¹Ú¼ö¿¬(Park Soo-Youn) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
À¯Çü¹Î(Yu Hyung-Min) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
±èÁö¿Ï(Kim Ji-Wan) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
¾È»óÈñ(An Sang-Hee) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
±è¿í¿¬(Kim Wook-Youn) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø º´¸®Çб³½Ç
Çã¹Ì³ª(Hur Mi-Na) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø Áø´Ü°Ë»çÀÇÇб³½Ç
ÀÌÈ«±â(Lee Hong-Gi) - °Ç±¹´ëÇб³ ÀÇÇÐÀü¹®´ëÇпø ³»°úÇб³½Ç
Abstract
Post-transplantation lymphoproliferative disorder (PTLD) is a serious complication that can develop after either solid organ or hematopoietic stem cell transplantation (HSCT). The incidence of Hodgkin¡¯s lymphoma (HL) ranges from 0.5-1.0% of PTLD after HSCT without T-cell depletion. Here, we report a case of HL-PTLD that occurred after autologous peripheral blood stem cell transplantation for an angioimmunoblastic T-cell lymphoma (AITL). A 36-year-old patient developed fever and chills with multiple lymphadenopathies at day 673 after auto-HSCT for AITL. Three months after the transplant, the patient developed fever with elevated plasma Epstein-Barr virus (EBV)-PCR values. The excisional biopsy revealed HL at Ann Arbor stage IIIB. A total of 8 cycles of chemotherapy with ABVD please define were performed, and the patient has remained disease-free. To our knowledge, this is first case report of HL-PTLD after auto-PBSCT in Korea.
Å°¿öµå
Lymphoproliferative disorder, Hodgkin disease, Hematopoietic stem cell transplantation, Epstein-Barr virus
KMID :
0882420140860060774
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)