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Splenic Infarction as the Initial Manifestation of Antiphospholipid Syndrome in a Systemic Lupus Erythematosus Patient

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Á¤ÇýÀ±(Jeong Hye-Yun) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú
°­»êÇÏ(Kang San-Ha) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú
¼ÛÁöÇö(Song Ji-Hyun) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú
½Å¼±¿µ(Shin Sun-Young) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú
¹Î´Ù´Ï¿¤(Min Daniel) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú
ÇѱÔÇö(Han Kyu-Hyun) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú
ÃÖÁøÁ¤(Choi Jin-Jung) - Â÷ÀǰúÇдëÇб³ ºÐ´çÂ÷º´¿ø ³»°ú

Abstract

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipid antibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complication of arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of left upper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhage and splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-day duration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenic infarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndrome that presented as a splenic infarction in a SLE patient.

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Lupus erythematosus, Systemic, Antiphospholipid syndrome, Splenic infarction
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