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Effective Treatment of Intractable Diarrhea Associated with Common Variable Immunodeficiency with Oral Budesonide
´ëÇѳ»°úÇÐȸÁö 2014³â 86±Ç 5È£ p.637 ~ p.640
ÀüÁöÇö(Jeon Ji-Hyun) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÓµµÇü(Lim Do-Hyoung) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹ÚâÇö(Park Chang-Hyun) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±ÇÇõÂù(Kwon Hyeok-Chan) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¤Áö¿¬(Jung Ji-Yun) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹Ú°Ç¿ì(Park Keon-Woo) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
À̼øÀÏ(Lee Soon-Il) - ´Ü±¹´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody deficiency syndrome and has a high prevalence of gastrointestinal complications. We report the case of a 36-year-old male with CVID who presented with chronic intractable diarrhea and malabsorption. A comprehensive evaluation revealed no secondary causes of his symptoms. He was treated symptomatically without improvement. After receiving systemic steroid treatment, his symptoms improved, but returned soon after tapering the steroid. When he was subsequently administered oral budesonide, his symptoms and quality of life improved; this effect lasted for 20 months without unacceptable side effects.
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Common variable immunodeficiency, Diarrhea, Steroid
KMID :
0882420140860050637
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