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A Gangliocytic Paraganglioma Presenting as a Submucosal Tumor in the Ampulla

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¾çÀçÈÆ(Yang Jae-Hoon) - °Ç±¹´ëÇб³ Àǰú´ëÇÐ ³»°úÇб³½Ç
õ¿µ±¹(Cheon Young-Kook) - °Ç±¹´ëÇб³ Àǰú´ëÇÐ ³»°úÇб³½Ç
ÀÌÅÂÀ±(Lee Tae-Yoon) - °Ç±¹´ëÇб³ Àǰú´ëÇÐ ³»°úÇб³½Ç
½ÉÂù¼·(Shim Chan-Sup) - ¼øÃµÇâ´ëÇб³º´¿ø ³»°úÇб³½Ç
±è¿í¿¬(Kim Wook-Youn) - °Ç±¹´ëÇб³ Àǰú´ëÇÐ º´¸®Çб³½Ç

Abstract

A gangliocytic paraganglioma (GP) is a rare benign neuroendocrine tumor. However, its origin remains unclear. It is seen most frequently in the second portion of the duodenum. At endoscopy, a GP characteristically appears as a pedunculated nodular submucosal tumor with erosions and surface ulcers. The histological diagnosis is usually made from endoscopic biopsies showing the presence of epithelioid, spindle, and ganglion cells. We experienced a case of GP in a 38-year-old female who was referred because of a possible ampullary tumor. The endoscopic images showed a 1.5-cm, oval ampullary tumor covered with normal mucosa. An endoscopic biopsy showed chronic duodenitis. The tumor was removed by an endoscopic papillectomy. We report a case of duodenal GP that presented as a submucosal tumor that was treated with a papillectomy and review the literature.

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Paraganglioma, Gangliocytic, Endoscopic mucosal resection
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DOI
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ICD 03
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