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중증 폐기종 환자에서 내시경적 폐용적 축소술의 임상 적용
Clinical Applications of Bronchoscopic Lung Volume Reduction for Patients with Severe Emphysema

대한내과학회지 2014년 86권 4호 p.432 ~ p.437

박태선(Park Tai-Sun) - 울산대학교 의과대학 서울아산병원 호흡기내과
이세원(Lee Sei-Won) - 울산대학교 의과대학 서울아산병원 호흡기내과

Abstract

Emphysema is a category of chronic obstructive pulmonary disease characterized by chronic airflow limitation and hyperinflation. Several decades ago, it was found that the surgical resection of emphysematous lung improved lung function and the long-term survival in patients with severe advanced emphysema. However, it was associated with substantial postoperative morbidity, such as persistent air-leak and mortality. Therefore, bronchoscopic lung volume reduction (BLVR) techniques have been developed to avoid these risks associated with surgery. Of these, endobronchial valves have been subject to the largest number of clinical trials. Endobronchial valves are unidirectional valves placed in the bronchus of the most hyperinflated lobe to block regional inflation, while allowing exhalation, leading to atelectasis of the target lobe. BLVR using endobronchial valves improves lung function, exercise tolerance, and symptoms. To obtain the maximum clinical benefits, it is important to select patients who have a complete lobar fissure and heterogeneous emphysematous lung involvement. Other bronchoscopic approaches are being developed to overcome these limitations.

키워드

Emphysema, Chronic obstructive pulmonary disease, Lung volume reduction, Bronchoscopy

KMID : 0882420140860040432

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DOI

KCD코드

ICD 03

건강보험코드

중증 폐기종 환자에서 내시경적 폐용적 축소술의 임상 적용 Clinical Applications of Bronchoscopic Lung Volume Reduction for Patients with Severe Emphysema

Abstract

키워드

중증 폐기종 환자에서 내시경적 폐용적 축소술의 임상 적용
Clinical Applications of Bronchoscopic Lung Volume Reduction for Patients with Severe Emphysema