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A Case of Cryptococcal Myofascitis in a Patient with Iatrogenic Cushing¡¯s Syndrome

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Á¤Áö¿ø(Jung Ji-Won) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
Àü¹ÌÁ¤(Jun Mi-Jung) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
½ÅÀºÇý(Shin Eun-Hye) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
¾ç¿µÁÖ(Yang Young-Joo) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
Á¶ÇüÁø(Cho Hyung-Jin) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
±è¹Ì³ª(Kim Mi-Na) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø Áø´Ü°Ë»çÀÇÇаú
ÀÌ»ó¿À(Lee Sang-Oh) - ¿ï»ê´ëÇб³ Àǰú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç

Abstract

The skin is the third most common site of cryptococcosis after infections of the central nervous system and lungs. However, cryptococcosis rarely involves deep soft tissue. Here, we report a case of cryptococcal cellulitis and myofascitis in a 72-year-old woman with iatrogenic Cushing¡¯s syndrome. Despite the administration of antibiotics, the patient continued to suffer from aggravated wounds and pain. Cultures of pus and an excisional biopsy of the skin revealed Cryptococcus neoformans. She was treated successfully with intravenous fluconazole (400 mg/day) for 14 days followed by oral fluconazole (400 mg/day) for 12 months.

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Crytptococcus neoformans, Cellulitis, Myositis, Cushing¡¯s syndrome
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