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A Case of Primaquine-Induced Acute Liver Failure
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Àü¹ÌÁ¤(Jun Mi-Jung) - ¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
À̴ܺñ(Lee Dan-Bi) - ¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
ÃÖÀ±½Ä(Choi Yun-Sik) - ¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¾Æ»êº´¿ø ³»°ú
±èÀºÁø(Kim Eun-Jin) - ¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¾Æ»êº´¿ø ³»°ú
°øÀºÁ¤(Gong Eun-Jeong) - ¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¾Æ»êº´¿ø ³»°úÇб³½Ç
Á¤¿µÈ(Chung Young-Hwa) - ¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼¿ï¾Æ»êº´¿ø ³»°ú
Abstract
Primaquine was approved for treatment of malaria in 1952 by the United States Food and Drug Administration (FDA). It has remained the only FDA-licensed drug capable of clearing the intra-hepatic schizonts and hypnozoites of Plasmodium vivax. It is associated with serious hazards and side effects, such as hemolytic anemia and methemoglobinemia. However, there is no report of primaquine causing liver injury in Korea. We describe a case of acute liver failure following primaquine overdose in a 19-year-old man.
Å°¿öµå
Primaquine, Drug-induced liver injury, Liver failure, Acute
KMID :
0882420140860010054
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