Radiofrequency Ablation Using a Monopolar Wet Electrode for the Treatment of Inoperable Non-Small Cell Lung Cancer: a Preliminary Report

Korean Journal of Radiology 2008년 9권 2호 p.140 ~ p.147

진공용(Jin Gong-Yong) - 전북대학교 의과대학 방사선학교실
한영민(Han Young-Min) - 전북대학교 의과대학 영상의학교실
이영선(Lee Young-Sun) - 전북대학교 의과대학 방사선학교실
이용철(Lee Yong-Chul) - 전북대학교 의과대학 내과학교실


Objective : To assess the technical feasibility and complications of radiofrequency ablation (RFA) using a monopolar wet electrode for the treatment of inoperable non-small cell lung malignancies.

Materials and Methods : Sixteen patients with a non-small cell lung malignancy underwent RFA under CT guidance. All the patients were non-surgical candidates, with mean maximum tumor diameters ranging from 3 to 6 cm (mean: 4.6 +/- 1.1 cm). A single 16-gauge open-perfused electrode with a 2 cm exposed tip was used for the procedure. A 0.9% NaCl saline solution was used as the perfusion liquid with the flow adjusted to 30 mL/h. The radiofrequency energy was applied for 10-40 minutes. The response to RFA was evaluated by performing contrast-enhanced CT immediately after RFA, one month after treatment and then every three months thereafter.

Results : Technical failure was observed in six (37.5%) of 16 patients: intractable pain (n = 2) and non-stop coughing (n = 4). The mean follow-up interval was 15 +/- 8 months (range: 9-31 months). The mean maximum ablated diameter in the technically successful group of patients ranged from 3.5 to 7.5 cm (mean 5.1 +/- 1.3 cm). Complete necrosis was attained for eight (80%) of 10 lesions, and partial necrosis was achieved for two lesions. There were two major complications (2/10, 20%) encountered: a hemothorax (n = 1) and a bronchopleural fistula (n = 1).

Conclusion : Although RFA using a monopolar wet electrode can create a large ablation zone, it is associated with a high rate of technical failure when used to treat inoperable non-small cell lung malignancies.


Radiofrequency (RF) ablation, Lung neoplasm, Lung, interventional procedure, Lung, CT
원문 및 링크아웃 정보
등재저널 정보
SCI(E) MEDLINE 학술진흥재단(KCI) KoreaMed 대한의학회 회원 
주제명(Target field)
연구참여(Sample size)
질병특성(Condition Category)
연구설계(Study Design)
중재방법(Intervention Type)
중재명칭(Intervention Name)
This technique showed a high rate of technical failure due to side effects such as pain and cough during the RFA procedure. There were also limitations in achieving complete necrosis due to the irregular shape of the created ablation zones, as shown on the follow-up CT.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
ICD 03