Radiofrequency Ablation Using a Monopolar Wet Electrode for the Treatment of Inoperable Non-Small Cell Lung Cancer: a Preliminary Report
Korean Journal of Radiology 2008³â 9±Ç 2È£ p.140 ~ p.147
Áø°ø¿ë(Jin Gong-Yong) - ÀüºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ¹æ»ç¼±Çб³½Ç
ÇÑ¿µ¹Î(Han Young-Min) - ÀüºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ¿µ»óÀÇÇб³½Ç
ÀÌ¿µ¼±(Lee Young-Sun) - ÀüºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ¹æ»ç¼±Çб³½Ç
ÀÌ¿ëö(Lee Yong-Chul) - ÀüºÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
Objective : To assess the technical feasibility and complications of radiofrequency ablation (RFA) using a monopolar wet electrode for the treatment of inoperable non-small cell lung malignancies.
Materials and Methods : Sixteen patients with a non-small cell lung malignancy underwent RFA under CT guidance. All the patients were non-surgical candidates, with mean maximum tumor diameters ranging from 3 to 6 cm (mean: 4.6 +/- 1.1 cm). A single 16-gauge open-perfused electrode with a 2 cm exposed tip was used for the procedure. A 0.9% NaCl saline solution was used as the perfusion liquid with the flow adjusted to 30 mL/h. The radiofrequency energy was applied for 10-40 minutes. The response to RFA was evaluated by performing contrast-enhanced CT immediately after RFA, one month after treatment and then every three months thereafter.
Results : Technical failure was observed in six (37.5%) of 16 patients: intractable pain (n = 2) and non-stop coughing (n = 4). The mean follow-up interval was 15 +/- 8 months (range: 9-31 months). The mean maximum ablated diameter in the technically successful group of patients ranged from 3.5 to 7.5 cm (mean 5.1 +/- 1.3 cm). Complete necrosis was attained for eight (80%) of 10 lesions, and partial necrosis was achieved for two lesions. There were two major complications (2/10, 20%) encountered: a hemothorax (n = 1) and a bronchopleural fistula (n = 1).
Conclusion : Although RFA using a monopolar wet electrode can create a large ablation zone, it is associated with a high rate of technical failure when used to treat inoperable non-small cell lung malignancies.
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Radiofrequency (RF) ablation, Lung neoplasm, Lung, interventional procedure, Lung, CT
KMID :
0880420080090020140
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This technique showed a high rate of technical failure due to side effects such as pain and cough during the RFA procedure. There were also limitations in achieving complete necrosis due to the irregular shape of the created ablation zones, as shown on the follow-up CT.