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Recovery Effect of Blending Oil on Skin Barrier Damaged by Atopic Dermatitis
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Abstract
Purpose: The purpose of this study was to evaluate the effect of a mixture of ARL oils, Agastache rugosa, Rosemarinu officinalis, and Lavandula angustifolia on atopic dermatitis (AD) model on NC/Nga mice.
Methods: Twenty-four, 6 week-NC/Nga mice were assigned to a control group (C, n=8), an AD-induced group (E, n=8), and an ARL oil-treated group (E, n=8) that had two treatments per day for 6 days. Epidermis thickness, total amount of collagen and expression of TGF-¥â in the AD induced mice were measured.
Results: The ARL oil-treated group showed a significantly decreased epidermis thickness, and a greater amount of collagen and expression of TGF-¥â compared with the AD-induced group.
Conclusison: ARL oil may be a putative resources for care or treatment of AD in the view of nursing intervention.
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Atopic dermatitis, Essential oil, Skin
KMID :
0869520140200010057
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