¿©Æ÷¼º Á¾¾ç ¶Ç´Â ÈÖƲ¼¼Æ÷ Á¾¾ç¿¡¼ ¾ÏÀÇ Áø´Ü¿¡ ÀÖ¾î ¼ö¼úÀü Ç÷û °©»ó¼±±Û·ÎºÒ¸°ÀÇ Áø´ÜÀû °¡Ä¡
Diagnostic Value of Preoperative Serum Thyroglobulin Measurement for the Diagnosis of Malignancy in Follicular or Hurthle Cell Neoplasms of the Thyroid Gland
°í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ÇмúÁö 2014³â 29±Ç 1È£ p.17 ~ p.22
±è³²±Ô(Kim Nam-Kyu) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
°¼ºÁÖ(Kang Seong-Joo) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÀÌ¿øÇü(Lee Weon-Hyoung) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¿©°íÀº(Yeo Go-Eun) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÇÑÀ¯Áø(Han You-Jin) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±èºÎ°æ(Kim Bu-Kyung) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±Ç¼ö°æ(Kwon Su-Kyoung) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
¹Ú¿äÇÑ(Park Yo-Han) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
ÃÖ¿µ½Ä(Choi Young-Sik) - °í½Å´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Abstract
Objectives: The aim of this retrospective study was whether serum Tg predicts malignancy in follicular or Hurthle-cell neoplasms on fine needle aspiration.
Methods: A chart review of 111 patients (90 females, 21 males; mean age 46.8 ¡¾ 11.9 years) with follicular or Hurthle-cell neoplasms on fine needle aspiration, who were surgically treated between Sep. 2001 and Sep. 2011, was performed. Predictive factors for malignancy were identified by the chi-squared test and multivariate logistic regression.
Results: There were no differences between 41 malignant and 70 benign lesions in serum Tg or any of the normalized indexes. Receiver-operator characteristic analysis revealed no cut-off value. Lesions with serum Tg levels greater than 500 g/L had no significant difference. And also there were no independent predictors of malignancy by multivariate logistic regression.
Conclusions: In this study, the author found that serum Tg has poor accuracy for predicting malignancy in follicular or Hurthle cell neoplasms on fine needle aspiration.
Å°¿öµå
Follicular neoplasm, Hurthle cell neoplasm, Serum thyroglobulin, Thyroid carcinoma
KMID :
0857020140290010017
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)