Estimating the Burden of Irritable Bowel Syndrome: Analysis of a Nationwide Korean Database

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Á¤Çý°æ(Jung Hye-Kyung) - Ewha Womans University School of Medicine Department of Internal Medicine
±è¿¬Èñ(Kim Youn-Hee) - National Evidence-Based Healthcare Collaborating Agency
¹ÚÁÖ¿¬(Park Joo-Yeon) - National Evidence-Based Healthcare Collaborating Agency
À庸Çü(Jang Bo-Hyoung) - National Evidence-Based Healthcare Collaborating Agency
¹Ú¼±¿µ(Park Sun-Young) - National Evidence-Based Healthcare Collaborating Agency
³²¹ÌÈñ(Nam Mi-Hee) - National Evidence-Based Healthcare Collaborating Agency
ÃÖ¸í±Ô(Choi Myung-Gyu) - Catholic University College of Medicine Department of Internal Medicine

Abstract

Background/Aims: Management of irritable bowel syndrome (IBS) imposes a heavy economic burden. This study was to estimate the epidemio-logic features of IBS and to report the IBS burden for the first time in the Korean population.

Methods: A cross-sectional study was conducted using the National Health Insurance (NHI) system database, which covers the entire pop-ulation of Korea. IBS was defined as diagnostic code -10 in adults with any outpatient clinic visits or hospitalization related to IBS. We excluded diseases that mimic IBS symptoms.

Results: A total of 2.42 million (58.2% female) individuals were identified as patients with IBS, yielding an age- and gender-adjusted prevalence of 5.1% in males and 6.9% in females. The prevalence of IBS increased proportionally with age, with higher medical costs in middle-aged patients. Outpatient clinics were visited by 98.6% of IBS patients, and 1.9% were treated upon admission. Of these patients, 87.6% were given a prescription. Co-morbidities that commonly accompanied IBS included upper gastro-intestinal (36.1%), respiratory (12.3%), musculoskeletal (8.0%) disease, somatoform (4.3%) and depression/anxiety disorders (3.1%). The NHI costs of IBS, which include the NHI covered cost and beneficiary copayment charges, were estimated to be 155 million USD, which accounts for 0.46% of the total NHI costs for the entire Korean population.

Conclusions:According to the Korean national claims database, about 6% of the Korean population seeks medical care for IBS at least once per year. This high prevalence places a large economic burden on the Korean healthcare system, accounting for 0.46% of over-all national medical expenditure.

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Epidemiology, Cost of illness, Irritable bowel syndrome, Population
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