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Cardiovascular Disease in Pediatric Chronic Kidney Disease
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Abstract
¸¸¼º ÄáÆϺ´ÀÇ Àå±â ¿¹Èĸ¦ °áÁ¤ÇÏ´Â ¿äÀÎ Áß ½ÉÇ÷°ü°èÇÕº´ÁõÀÇ Á߿伺Àº Àß ¾Ë·ÁÁ® ÀÖ´Ù. ±×·¯³ª ¼Ò¾Æ ȯÀÚÀÇ °æ¿ì ÀüÇüÀûÀÎ Áõ»ó ¹ßÇöÀÌ Àû¾î ±× ÀÓ»óÀû Á߿伺ÀÌ °£°úµÇ´Â °æÇâÀÌ ÀÖ´Ù. ÇöÀç±îÁö ¾Ë·ÁÁø ½ÉÇ÷°ü°è ÇÕº´ÁõÀÇ À§ÇèÀÎÀڷδ °íÇ÷¾Ð, ´ç´¢º´, ÀÌ»óÁöÁúÇ÷Áõ, ºñ¸¸°ú °°Àº ÀüÅëÀûÀÎ À§Çè ÀÎÀÚ¿Í ºóÇ÷, ÀÌÂ÷¼º ºÎ°©»ó¼± ±â´ÉÇ×ÁøÁõ, »êÈ ½ºÆ®·¹½º, ¿°Áõ°ú °°Àº »õ·Î¿î À§Çè ÀÎÀÚ µîÀÌ ¾Ë·ÁÁ® ÀÖ´Ù.
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Cardiovascular disease (CVD) has been identified as one of the most importantfactors influencing the long-term prognosis of patients with chronic kidneydisease (CKD). However, in pediatric CKD, the clinical importance of CVD tendsto be overlooked due to the lack of typical manifestations of CVD in this population.
The literature has identified several traditional risk factors of CVD thatoriginate from CKD, including hypertension, diabetes mellitus, dyslipidemia andobesity, in addition to new and non-traditional risk factors including anemia,secondary hyperparathyroidism, oxidative stress and inflammation. In cases ofpediatric CKD, cardiovascular disease is usually restricted to subclinical manifestationssuch as left ventricular hypertrophy, thickening of intimal media onthe carotid artery and calcification of the coronary artery. Therefore, risk factorsof CVD in pediatric CKD patients should be closely monitored.
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Cardiovascular disease, Children, Chronic kidney disease
KMID :
0811820140180010007
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